Cleaved-KLK11 (I54) Antibody (PACO00030)
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주문- SKU:
- PACO00030
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | Cleaved-KLK11 (I54) Antibody |
Antibody SKU: | PACO00030 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the Internal region of human KLK11. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | KLK11; PRSS20; TLSP; Kallikrein-11; hK11; Hippostasin; Serine protease 20; Trypsin-like protease |
UniProt Protein Function: | KLK11: Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues. Belongs to the peptidase S1 family. Kallikrein subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.4.21.-; Protease; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 19q13.41 Cellular Component: extracellular space Molecular Function:serine-type peptidase activity |
NCBI Summary: | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed. [provided by RefSeq, Dec 2016] |
UniProt Code: | Q9UBX7 |
NCBI GenInfo Identifier: | 88984315 |
NCBI Gene ID: | 11012 |
NCBI Accession: | Q9UBX7.2 |
UniProt Secondary Accession: | Q9UBX7,O75837, Q0WXX5, Q8IXD7, Q9NS65, |
UniProt Related Accession: | Q9UBX7 |
Molecular Weight: | 31kDa |
NCBI Full Name: | Kallikrein-11 |
NCBI Synonym Full Names: | kallikrein related peptidase 11 |
NCBI Official Symbol: | KLK11 |
NCBI Official Synonym Symbols: | TLSP; PRSS20 |
NCBI Protein Information: | kallikrein-11 |
UniProt Protein Name: | Kallikrein-11 |
UniProt Synonym Protein Names: | Hippostasin; Serine protease 20; Trypsin-like protease |
Protein Family: | Kallikrein |
UniProt Gene Name: | KLK11 |