Cleaved-CTSG (I21) Antibody (PACO00023)
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주문- SKU:
- PACO00023
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | Cleaved-CTSG (I21) Antibody |
Antibody SKU: | PACO00023 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from the N-terminal region of human Cathepsin G. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | CTSG; Cathepsin G; CG |
UniProt Protein Function: | CTSG: Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. Belongs to the peptidase S1 family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; EC 3.4.21.20; Protease Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: extracellular matrix; extracellular space; cell surface; extracellular region; plasma membrane; nucleus; secretory granule Molecular Function:heparin binding; peptidase activity; serine-type endopeptidase activity Biological Process: extracellular matrix disassembly; positive regulation of immune response; extracellular matrix organization and biogenesis; cellular protein metabolic process; response to lipopolysaccharide; immune response; protein processing; proteolysis; angiotensin maturation; defense response to fungus |
NCBI Summary: | The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014] |
UniProt Code: | P08311 |
NCBI GenInfo Identifier: | 115725 |
NCBI Gene ID: | 1511 |
NCBI Accession: | P08311.2 |
UniProt Secondary Accession: | P08311,Q6IBJ6, Q9UCA5, Q9UCU6, |
UniProt Related Accession: | P08311 |
Molecular Weight: | 255 |
NCBI Full Name: | Cathepsin G |
NCBI Synonym Full Names: | cathepsin G |
NCBI Official Symbol: | CTSG |
NCBI Official Synonym Symbols: | CG; CATG |
NCBI Protein Information: | cathepsin G |
UniProt Protein Name: | Cathepsin G |
Protein Family: | Cathepsin |
UniProt Gene Name: | CTSG |
UniProt Entry Name: | CATG_HUMAN |