CLDND1 Antibody (PACO14274)
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주문- SKU:
- PACO14274
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CLDND1 Antibody (PACO14274) |
Antibody SKU: | PACO14274 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human CLDND1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO14274(CLDND1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hepg2 cells, K562 cells, Primary antibody: PACO14274(CLDND1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14274(CLDND1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid, multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. |
Synonyms: | claudin domain containing 1 |
UniProt Protein Function: | CLDND1: Belongs to the PMP-22/EMP/MP20 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 3q12.1 Cellular Component: cell surface; apical plasma membrane; integral to membrane |
UniProt Code: | Q9NY35 |
NCBI GenInfo Identifier: | 20532022 |
NCBI Gene ID: | 56650 |
NCBI Accession: | Q9NY35.1 |
UniProt Secondary Accession: | Q9NY35,Q502Y8, Q6UVX2, Q9BUZ9, Q9NZZ5, Q9Y4S9, B3KQR1 D3DN36, F2Z2D9, |
UniProt Related Accession: | Q9NY35 |
Molecular Weight: | 253 |
NCBI Full Name: | Claudin domain-containing protein 1 |
NCBI Synonym Full Names: | claudin domain containing 1 |
NCBI Official Symbol: | CLDND1 |
NCBI Official Synonym Symbols: | C3orf4; GENX-3745 |
NCBI Protein Information: | claudin domain-containing protein 1; membrane protein GENX-3745; claudin domain containing 1 protein |
UniProt Protein Name: | Claudin domain-containing protein 1 |
UniProt Synonym Protein Names: | Membrane protein GENX-3745 |
Protein Family: | Claudin domain-containing protein |
UniProt Gene Name: | CLDND1 |
UniProt Entry Name: | CLDN1_HUMAN |
Antibodies |
Anti-CLDND1 Antibody (CAB2945) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |