CLCN6 Antibody (PACO06355)
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주문- SKU:
- PACO06355
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Reactivity:
- Monkey
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | CLCN6 Antibody (PACO06355) |
Antibody SKU: | PACO06355 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:40000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat, Monkey |
Immunogen: | Synthesized peptide derived from the Internal region of human CLC-6. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot analysis of K562 cells using CLC-6 Polyclonal Antibody. | |
Western Blot analysis of L929 cells using CLC-6 Polyclonal Antibody. |
Synonyms: | CLCN6; KIAA0046; Chloride transport protein 6; Chloride channel protein 6; ClC-6 |
UniProt Protein Function: | Function: Chloride transport protein, initially identified as voltage-gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter. |
UniProt Protein Details: | Subcellular location: Endosome membrane; Multi-pass membrane protein. Note: Detected in detergent-resistant lipid rafts. Ref.11 Tissue specificity: Testis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform 3 is only detected in kidney. Ref.1 Ref.2 Ref.10 Post-translational modification: N-glycosylated on several asparagine residues. Ref.11 Miscellaneous: The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters By similarity. Sequence similarities: Belongs to the chloride channel (TC 2.A.49) family. ClC-6/CLCN6 subfamily. [View classification]Contains 2 CBS domains. |
NCBI Summary: | This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional alternately spliced variants have been described but their full-length structure is unknown. [provided by RefSeq, Mar 2012] |
UniProt Code: | P51797 |
NCBI GenInfo Identifier: | 4502873 |
NCBI Gene ID: | 1185 |
NCBI Accession: | NP_001277 |
UniProt Related Accession: | P51797 |
Molecular Weight: | 93kDa |
NCBI Full Name: | chloride transport protein 6 isoform 1 |
NCBI Synonym Full Names: | chloride voltage-gated channel 6 |
NCBI Official Symbol: | CLCN6 |
NCBI Official Synonym Symbols: | CLC-6 |
NCBI Protein Information: | chloride transport protein 6 |
UniProt Protein Name: | Chloride transport protein 6 |
UniProt Synonym Protein Names: | Chloride channel protein 6 |
Protein Family: | Chloride transport protein |
UniProt Gene Name: | CLCN6 |
UniProt Entry Name: | CLCN6_HUMAN |
Antibodies |
Anti-CLCN6 Antibody (CAB17458) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |