CHD5 Antibody (PACO23523)
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주문- SKU:
- PACO23523
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CHD5 Antibody (PACO23523) |
Antibody SKU: | PACO23523 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide corresponding to residues near the C terminal of human Cadherin 5, type 2 (vascular endothelium) |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemical analysis of paraffin-embedded Human tonsil cancer tissue using at dilution 1/40. | |
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/40. |
Background: | This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. |
Synonyms: | 7B4; CD144 |
UniProt Protein Function: | CHD-5: May play a role in the development of the nervous system and the pathogenesis of neural tumors. Belongs to the SNF2/RAD54 helicase family. |
UniProt Protein Details: | Protein type:EC 3.6.4.12; DNA-binding; Tumor suppressor; Helicase Chromosomal Location of Human Ortholog: 1p36.31 Cellular Component: heterochromatin; membrane; nucleus; NuRD complex Biological Process: cerebral cortex neuron differentiation; negative regulation of cell proliferation; spermatogenesis, exchange of chromosomal proteins |
NCBI Summary: | This gene encodes a member of the chromodomain helicase DNA-binding protein family. Members of this family are characterized by a chromodomain, a helicase ATP-binding domain and an additional functional domain. This gene encodes a neuron-specific protein that may function in chromatin remodeling and gene transcription. This gene is a potential tumor suppressor gene that may play a role in the development of neuroblastoma. [provided by RefSeq, Feb 2012] |
UniProt Code: | Q8TDI0 |
NCBI GenInfo Identifier: | 51701343 |
NCBI Gene ID: | 26038 |
NCBI Accession: | Q8TDI0.1 |
UniProt Secondary Accession: | Q8TDI0,O75032, Q5TG89, Q7LGH2, Q9UFR9, |
UniProt Related Accession: | Q8TDI0 |
Molecular Weight: | 223,050 Da |
NCBI Full Name: | Chromodomain-helicase-DNA-binding protein 5 |
NCBI Synonym Full Names: | chromodomain helicase DNA binding protein 5 |
NCBI Official Symbol: | CHD5 |
NCBI Official Synonym Symbols: | CHD-5 |
NCBI Protein Information: | chromodomain-helicase-DNA-binding protein 5 |
UniProt Protein Name: | Chromodomain-helicase-DNA-binding protein 5 |
UniProt Synonym Protein Names: | ATP-dependent helicase CHD5 |
Protein Family: | Chromodomain-helicase-DNA-binding protein |
UniProt Gene Name: | CHD5 |
UniProt Entry Name: | CHD5_HUMAN |
Antibodies | ELISA Kits |
Anti-CHD5 Antibody (CAB8578) | Human CHD5 (Chromodomain Helicase DNA Binding Protein 5) ELISA Kit (HUES01883) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |