CGGBP1 Antibody (PACO42322)
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주문- SKU:
- PACO42322
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CGGBP1 Antibody (PACO42322) |
Antibody SKU: | PACO42322 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human CGG triplet repeat-binding protein 1 protein (1-167AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO42322 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO42322 at dilution of 1:100. |
Background: | Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter. |
Synonyms: | CGG triplet repeat-binding protein 1 (CGG-binding protein 1) (20 kDa CGG-binding protein) (p20-CGGBP DNA-binding protein), CGGBP1, CGGBP |
UniProt Protein Function: | CGGBP1: Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter. |
UniProt Protein Details: | Protein type:Transcription regulation Chromosomal Location of Human Ortholog: 3p11.1 Cellular Component: nucleoplasm; nucleus Molecular Function:double-stranded DNA binding; protein binding Biological Process: negative regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9UFW8 |
NCBI GenInfo Identifier: | 116243045 |
NCBI Gene ID: | 8545 |
NCBI Accession: | Q9UFW8.2 |
UniProt Secondary Accession: | Q9UFW8,O15183, D3DU38, |
UniProt Related Accession: | Q9UFW8 |
Molecular Weight: | 18,820 Da |
NCBI Full Name: | CGG triplet repeat-binding protein 1 |
NCBI Synonym Full Names: | CGG triplet repeat binding protein 1 |
NCBI Official Symbol: | CGGBP1 |
NCBI Official Synonym Symbols: | CGGBP; p20-CGGBP |
NCBI Protein Information: | CGG triplet repeat-binding protein 1 |
UniProt Protein Name: | CGG triplet repeat-binding protein 1 |
UniProt Synonym Protein Names: | 20 kDa CGG-binding protein; p20-CGGBP DNA-binding protein |
Protein Family: | CGG triplet repeat-binding protein |
UniProt Gene Name: | CGGBP1 |
UniProt Entry Name: | CGBP1_HUMAN |