CEP55 Antibody (PACO16014)
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주문- SKU:
- PACO16014
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CEP55 Antibody (PACO16014) |
Antibody SKU: | PACO16014 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
Species Reactivity: | Human, Rat |
Immunogen: | Fusion protein of human CEP55 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: PACO16014(CEP55 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes. |
Background: | Centrosomal protein of 55 kDa is a protein that in humans is encoded by the CEP55 gene. CEP55 is a mitotic phosphoprotein that plays a key role in cytokinesis, the final stage of cell division. Interacts (phosphorylated on Ser-425 and Ser-428) with PLK1. Interacts with AKAP9; the interaction occurs in interphase and is lost upon mitotic entry. Interacts with PCNT; the interaction occurs in interphase and is lost upon mitotic entry. Interacts with PDCD6IP; the interaction is direct; CEP55 binds PDCD6IP in a 2:1 stoechiometry; PDCD6IP competes with TSG101 for the same binding site. |
Synonyms: | centrosomal protein 55kDa |
UniProt Protein Function: | CEP55: Plays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA); Cell cycle regulation Chromosomal Location of Human Ortholog: 10q23.33 Cellular Component: centrosome; membrane; midbody Molecular Function:protein binding Biological Process: cell separation during cytokinesis; cytokinesis after mitosis; establishment of protein localization; mitotic metaphase plate congression; nuclear organization and biogenesis |
UniProt Code: | Q53EZ4 |
NCBI GenInfo Identifier: | 296439403 |
NCBI Gene ID: | 55165 |
NCBI Accession: | Q53EZ4.3 |
UniProt Secondary Accession: | Q53EZ4,Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7 B2RDG8, |
UniProt Related Accession: | Q53EZ4 |
Molecular Weight: | 46,857 Da |
NCBI Full Name: | Centrosomal protein of 55 kDa |
NCBI Synonym Full Names: | centrosomal protein 55 |
NCBI Official Symbol: | CEP55 |
NCBI Official Synonym Symbols: | CT111; URCC6; C10orf3 |
NCBI Protein Information: | centrosomal protein of 55 kDa |
UniProt Protein Name: | Centrosomal protein of 55 kDa |
UniProt Synonym Protein Names: | Up-regulated in colon cancer 6 |
Protein Family: | Centrosomal protein |
UniProt Gene Name: | CEP55 |
UniProt Entry Name: | CEP55_HUMAN |
Antibodies |
Anti-CEP55 Antibody (CAB8229) |
CEP55 Antibody (PACO00583) |
Phospho-CEP55 (S425) Antibody (PACO04687) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |