CEACAM5 Antibody (PACO13766)
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주문- SKU:
- PACO13766
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CEACAM5 Antibody (PACO13766) |
Antibody SKU: | PACO13766 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human CEACAM5 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO13766(CEACAM5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human liver cancer tissue, Human lung cancer tissue, Primary antibody: PACO13766(CEACAM5 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO13766(CEACAM5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (Cluster ofDifferentiation 66e), is a human gene. Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. CD66E is a well known tumor marker and a heavily glycosylated GPI-linked cell surface molecule. |
Synonyms: | carcinoembryonic antigen-related cell adhesion molecule 5 |
UniProt Protein Function: | CEACAM5: Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. Belongs to the immunoglobulin superfamily. CEA family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Immunoglobulin superfamily; Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 19q13.1-q13.2 Cellular Component: basolateral plasma membrane; integral to plasma membrane Molecular Function:identical protein binding; protein homodimerization activity Biological Process: homotypic cell-cell adhesion; negative regulation of apoptosis |
NCBI Summary: | Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA gene family, see CEACAM1 (MIM 109770).[supplied by OMIM, Oct 2009] |
UniProt Code: | P06731 |
NCBI GenInfo Identifier: | 317373456 |
NCBI Gene ID: | 1048 |
NCBI Accession: | P06731.3 |
UniProt Secondary Accession: | P06731,H9KVA7, |
UniProt Related Accession: | P06731 |
Molecular Weight: | 76,795 Da |
NCBI Full Name: | Carcinoembryonic antigen-related cell adhesion molecule 5 |
NCBI Synonym Full Names: | carcinoembryonic antigen-related cell adhesion molecule 5 |
NCBI Official Symbol: | CEACAM5 |
NCBI Official Synonym Symbols: | CEA; CD66e |
NCBI Protein Information: | carcinoembryonic antigen-related cell adhesion molecule 5; meconium antigen 100 |
UniProt Protein Name: | Carcinoembryonic antigen-related cell adhesion molecule 5 |
UniProt Synonym Protein Names: | Carcinoembryonic antigen; CEA; Meconium antigen 100 |
Protein Family: | Colicin |
UniProt Gene Name: | CEACAM5 |
UniProt Entry Name: | CEAM5_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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