CDKL3 Antibody (PACO21892)
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주문- SKU:
- PACO21892
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CDKL3 Antibody (PACO21892) |
Antibody SKU: | PACO21892 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human CDKL3. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Greenman C., Nature 446:153-158(2007). |
Clonality: | Polyclonal |
Conjugate: | Non-conjugated |
Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using CDKL3 antibody. |
Synonyms: | Cyclin-dependent kinase-like 3; EC 2.7.11.22; Serine/threonine protein kinase NKIAMRE; CDKL3; NKIAMRE |
UniProt Protein Function: | CDKL3: a protein kinase of the CDKL family. Absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. The function of this gene has not yet been determined. |
UniProt Protein Details: | Protein type:Cell cycle regulation; Kinase, protein; Protein kinase, CMGC; EC 2.7.11.22; Protein kinase, Ser/Thr (non-receptor); CMGC group; CDKL family Chromosomal Location of Human Ortholog: 5q31 Molecular Function:protein binding; protein kinase activity Biological Process: protein modification process |
NCBI Summary: | The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8IVW4 |
NCBI GenInfo Identifier: | 74762479 |
NCBI Gene ID: | 51265 |
NCBI Accession: | Q8IVW4.1 |
UniProt Secondary Accession: | Q8IVW4,Q9P114, D3DQA0, D3DQA1, |
UniProt Related Accession: | Q8IVW4 |
Molecular Weight: | 51,566 Da |
NCBI Full Name: | Cyclin-dependent kinase-like 3 |
NCBI Synonym Full Names: | cyclin dependent kinase like 3 |
NCBI Official Symbol: | CDKL3 |
NCBI Official Synonym Symbols: | NKIAMRE |
NCBI Protein Information: | cyclin-dependent kinase-like 3 |
UniProt Protein Name: | Cyclin-dependent kinase-like 3 |
UniProt Synonym Protein Names: | Serine/threonine-protein kinase NKIAMRE |
Protein Family: | Cyclin-dependent kinase |
UniProt Gene Name: | CDKL3 |
UniProt Entry Name: | CDKL3_HUMAN |