UniProt Protein Function: | CDK5RAP3: Potential regulator of CDK5 activity. May be involved in cell proliferation. Regulates CDK5 activity via its interaction with CDK5R1. Belongs to the CDK5RAP3 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 17q21.32 Cellular Component: protein complex; membrane; cytoplasm; nucleolus; endomembrane system; nucleus Molecular Function:cyclin binding; protein binding; protein kinase binding Biological Process: cell proliferation; regulation of neuron differentiation; positive regulation of protein ubiquitination; inhibition of NF-kappaB transcription factor; regulation of mitotic cell cycle; positive regulation of transcription from RNA polymerase II promoter; brain development; regulation of cyclin-dependent protein kinase activity |
NCBI Summary: | This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013] |
UniProt Code: | Q96JB5 |
NCBI GenInfo Identifier: | 32129444 |
NCBI Gene ID: | 80279 |
NCBI Accession: | Q96JB5.2 |
UniProt Secondary Accession: | Q96JB5,Q53FA2, Q9H3F8, Q9H8G0, Q9HBR9, B7Z6N4, D3DTU1 D3DTU2, F5H3I5, |
UniProt Related Accession: | Q96JB5 |
Molecular Weight: | 506 |
NCBI Full Name: | CDK5 regulatory subunit-associated protein 3 |
NCBI Synonym Full Names: | CDK5 regulatory subunit associated protein 3 |
NCBI Official Symbol: | CDK5RAP3 |
NCBI Official Synonym Symbols: | C53; IC53; LZAP; HSF-27; MST016; PP1553; OK/SW-cl.114 |
NCBI Protein Information: | CDK5 regulatory subunit-associated protein 3; CDK5 regulatory subunit associated protein IC53-2; ischemic heart CDK5 activator-binding protein C53; LXXLL/leucine-zipper-containing ARFbinding protein |
UniProt Protein Name: | CDK5 regulatory subunit-associated protein 3 |
UniProt Synonym Protein Names: | CDK5 activator-binding protein C53; Protein HSF-27 |
Protein Family: | CDK5RAP3-like protein |
UniProt Gene Name: | CDK5RAP3 |
UniProt Entry Name: | CK5P3_HUMAN |