UniProt Protein Function: | CDK16: May play a role in signal transduction cascades in terminally differentiated cells. Found in a complex containing CABLES1, CDK17 and TDRD7. Interacts with YWHAH, YWHAQ and YWHAZ. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. |
UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; Cell cycle regulation; EC 2.7.11.22; Protein kinase, CMGC; Kinase, protein; CMGC group; CDK family; TAIRE subfamily; CDK/TAIRE subfamily Chromosomal Location of Human Ortholog: Xp11 Cellular Component: microtubule cytoskeleton; synaptic vesicle; extrinsic to internal side of plasma membrane; neuron projection; transport vesicle; cytoplasm; plasma membrane; cell junction Molecular Function:protein serine/threonine kinase activity; protein binding; cyclin-dependent protein kinase activity; ATP binding Biological Process: growth hormone secretion; exocytosis; regulation of cell cycle; spermatogenesis; protein amino acid phosphorylation; neurite development |
NCBI Summary: | The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009] |
UniProt Code: | Q00536 |
NCBI GenInfo Identifier: | 266425 |
NCBI Gene ID: | 5127 |
NCBI Accession: | Q00536.1 |
UniProt Secondary Accession: | Q00536,A8K280, B7Z7C8, J3KN74, J3KQP7, |
UniProt Related Accession: | Q00536 |
Molecular Weight: | 56,375 Da |
NCBI Full Name: | Cyclin-dependent kinase 16 |
NCBI Synonym Full Names: | cyclin-dependent kinase 16 |
NCBI Official Symbol: | CDK16 |
NCBI Official Synonym Symbols: | PCTK1; PCTAIRE; PCTAIRE1; PCTGAIRE |
NCBI Protein Information: | cyclin-dependent kinase 16; PCTAIRE-motif protein kinase 1; cell division protein kinase 16; serine/threonine-protein kinase PCTAIRE-1 |
UniProt Protein Name: | Cyclin-dependent kinase 16 |
UniProt Synonym Protein Names: | Cell division protein kinase 16; PCTAIRE-motif protein kinase 1; Serine/threonine-protein kinase PCTAIRE-1 |
UniProt Gene Name: | CDK16 |
UniProt Entry Name: | CDK16_HUMAN |