CDC40 Antibody (PACO22519)
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주문- SKU:
- PACO22519
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CDC40 Antibody (PACO22519) |
Antibody SKU: | PACO22519 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from internal of human CDC40. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from K562 cells, HUVEC cells and COLO cells, using CDC40 antibody. |
Background: | Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing. |
Synonyms: | cell division cycle 40; EH-binding protein 3; EHB3; pre-mRNA splicing factor 17; pre-mRNA-processing factor 17 |
UniProt Protein Function: | CDC40: Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.Protein type: Motility/polarity/chemotaxis; RNA processing; RNA splicing; SpliceosomeChromosomal Location of Human Ortholog: 6q21Cellular Component: nucleoplasm; nucleus; spliceosomal complexMolecular Function: protein binding; RNA bindingBiological Process: mRNA 3'-end processing; mRNA export from nucleus; mRNA splicing, via spliceosome; RNA export from nucleus; RNA splicing; termination of RNA polymerase II transcription |
UniProt Protein Details: | |
NCBI Summary: | Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008] |
UniProt Code: | O60508 |
NCBI GenInfo Identifier: | 7706657 |
NCBI Gene ID: | 51362 |
NCBI Accession: | NP_056975.1 |
UniProt Secondary Accession: | O60508,O75471, Q5SRN0, Q9UPG1, B2RBC5 |
UniProt Related Accession: | O60508 |
Molecular Weight: | 65,521 Da |
NCBI Full Name: | pre-mRNA-processing factor 17 |
NCBI Synonym Full Names: | cell division cycle 40 |
NCBI Official Symbol: | CDC40 |
NCBI Official Synonym Symbols: | EHB3; PRP17; PRPF17 |
NCBI Protein Information: | pre-mRNA-processing factor 17 |
UniProt Protein Name: | Pre-mRNA-processing factor 17 |
UniProt Synonym Protein Names: | Cell division cycle 40 homolog; EH-binding protein 3; Ehb3; PRP17 homolog; hPRP17 |
Protein Family: | Pre-mRNA-processing factor |
UniProt Gene Name: | CDC40 |
UniProt Entry Name: |
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