CD97 Antibody (PACO20376)
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주문- SKU:
- PACO20376
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CD97 Antibody (PACO20376) |
Antibody SKU: | PACO20376 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human CD97 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 8%SDS-PAGE,Lysate: 40 μgPrimary antibody: PACO20376(CD97 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 2 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20376(CD97 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. |
Synonyms: | CD97 molecule |
UniProt Protein Function: | CD97: Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:GPCR, family 2; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 19p13.12 Cellular Component: focal adhesion; integral to plasma membrane; membrane; plasma membrane Molecular Function:protein binding; transmembrane receptor activity Biological Process: cell motility; cell-cell signaling; immune response; inflammatory response |
NCBI Summary: | This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011] |
UniProt Code: | P48960 |
NCBI GenInfo Identifier: | 90110013 |
NCBI Gene ID: | 976 |
NCBI Accession: | P48960.4 |
UniProt Secondary Accession: | P48960,O00718, O76101, Q8NG72, Q8TBQ7, A8K7Z4, B2RBJ9 |
UniProt Related Accession: | P48960 |
Molecular Weight: | 86,628 Da |
NCBI Full Name: | CD97 antigen |
NCBI Synonym Full Names: | adhesion G protein-coupled receptor E5 |
NCBI Official Symbol: | ADGRE5 |
NCBI Official Synonym Symbols: | CD97; TM7LN1 |
NCBI Protein Information: | CD97 antigen |
UniProt Protein Name: | CD97 antigen |
UniProt Synonym Protein Names: | Leukocyte antigen CD97; CD_antigen: CD97 |
Protein Family: | CD97 antigen |
UniProt Gene Name: | CD97 |
UniProt Entry Name: | CD97_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |