CD58 Antibody (PACO42963)
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주문- SKU:
- PACO42963
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CD58 Antibody (PACO42963) |
Antibody SKU: | PACO42963 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Lymphocyte function-associated antigen 3 protein (40-220AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: Lymphocyte function-associated antigen 3 antibody at 2µg/ml. Lane 1: Hela whole cell lysate. Lane 2: Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 29, 27, 28 kDa. Observed band size: 29 kDa. | |
Immunohistochemistry of paraffin-embedded human thymus tissue using PACO42963 at dilution of 1:100. |
Background: | Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. |
Synonyms: | Lymphocyte function-associated antigen 3 (Ag3) (Surface glycoprotein LFA-3) (CD antigen CD58), CD58, LFA3 |
UniProt Protein Function: | Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. |
NCBI Summary: | This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009] |
UniProt Code: | P19256 |
NCBI GenInfo Identifier: | 126225 |
NCBI Gene ID: | 965 |
NCBI Accession: | P19256.1 |
UniProt Secondary Accession: | P19256,Q5U053, Q6IB65, Q96KI9, A8K7G5, |
UniProt Related Accession: | P19256 |
Molecular Weight: | 27,960 Da |
NCBI Full Name: | Lymphocyte function-associated antigen 3 |
NCBI Synonym Full Names: | CD58 molecule |
NCBI Official Symbol: | CD58 |
NCBI Official Synonym Symbols: | ag3; LFA3; LFA-3 |
NCBI Protein Information: | lymphocyte function-associated antigen 3 |
UniProt Protein Name: | Lymphocyte function-associated antigen 3 |
UniProt Synonym Protein Names: | Surface glycoprotein LFA-3; CD_antigen: CD58 |
Protein Family: | Lymphocyte function-associated antigen |
UniProt Gene Name: | CD58 |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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