CD3EAP Antibody (PACO22311)
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주문- SKU:
- PACO22311
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | CD3EAP Antibody (PACO22311) |
Antibody SKU: | PACO22311 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human CD3EAP. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from A549 cells, using CD3EAP antibody. |
Background: | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation. soform 2 has been described as a component of preformed T-cell receptor (TCR) complex. |
Synonyms: | antisense to ERCC-1; CAST; CD3-epsilon-associated protein; CD3e-associated protein; CD3EAP |
UniProt Protein Function: | ASE-1: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation. Belongs to the eukaryotic RPA34 RNA polymerase subunit family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nucleolus; Transcription initiation complex Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: nucleoplasm; mitochondrion; cytoplasm; nucleolus; RNA polymerase I transcription factor complex; chromosome; nucleus; DNA-directed RNA polymerase I complex Molecular Function:DNA-directed RNA polymerase activity Biological Process: negative regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; gene expression; transcription initiation from RNA polymerase I promoter; termination of RNA polymerase I transcription; regulation of gene expression, epigenetic; transmembrane receptor protein tyrosine kinase signaling pathway; rRNA transcription |
UniProt Code: | O15446 |
NCBI GenInfo Identifier: | 6912246 |
NCBI Gene ID: | 10849 |
NCBI Accession: | NP_036231.1 |
UniProt Secondary Accession: | O15446,Q32N11, Q7Z5U2, Q9UPF6, |
UniProt Related Accession: | O15446 |
Molecular Weight: | 54,986 Da |
NCBI Full Name: | DNA-directed RNA polymerase I subunit RPA34 |
NCBI Synonym Full Names: | CD3e molecule, epsilon associated protein |
NCBI Official Symbol: | CD3EAP |
NCBI Official Synonym Symbols: | ASE1; CAST; ASE-1; PAF49 |
NCBI Protein Information: | DNA-directed RNA polymerase I subunit RPA34; A34.5; antisense to ERCC 1; CD3E-associated protein; antisense to ERCC-1 protein; CD3 epsilon associated protein; CD3-epsilon-associated protein; RNA polymerase I-associated factor PAF49; CD3e antigen, epsilon |
UniProt Protein Name: | DNA-directed RNA polymerase I subunit RPA34 |
UniProt Synonym Protein Names: | A34.5; Antisense to ERCC-1 protein; ASE-1; CD3-epsilon-associated protein; CAST; CD3E-associated protein; RNA polymerase I-associated factor PAF49 |
Protein Family: | Calpastatin |
UniProt Gene Name: | CD3EAP |
UniProt Entry Name: | RPA34_HUMAN |