CD180 Antibody (PACO06913)
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주문- SKU:
- PACO06913
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CD180 Antibody (PACO06913) |
Antibody SKU: | PACO06913 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from the Internal region of human CD180. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot analysis of mouse brain cells using CD180 Polyclonal Antibody. | |
Western Blot analysis of MOUSE-BRAIN cells using CD180 Polyclonal Antibody. |
Synonyms: | CD180; LY64; RP105; CD180 antigen; Lymphocyte antigen 64; Radioprotective 105 kDa protein; CD180 |
UniProt Protein Function: | CD180: May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells. Belongs to the Toll-like receptor family. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 5q12.3 Cellular Component: integral to plasma membrane Molecular Function:receptor activity Biological Process: inflammatory response; positive regulation of lipopolysaccharide-mediated signaling pathway; toll-like receptor signaling pathway |
NCBI Summary: | CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99467 |
NCBI GenInfo Identifier: | 296434437 |
NCBI Gene ID: | 4064 |
NCBI Accession: | Q99467.2 |
UniProt Secondary Accession: | Q99467,Q32MM5, B2R7Z7, |
UniProt Related Accession: | Q99467 |
Molecular Weight: | 74kDa |
NCBI Full Name: | CD180 antigen |
NCBI Synonym Full Names: | CD180 molecule |
NCBI Official Symbol: | CD180 |
NCBI Official Synonym Symbols: | LY64; Ly78; RP105 |
NCBI Protein Information: | CD180 antigen |
UniProt Protein Name: | CD180 antigen |
UniProt Synonym Protein Names: | Lymphocyte antigen 64; Radioprotective 105 kDa protein; CD_antigen: CD180 |
Protein Family: | CD180 antigen |
UniProt Gene Name: | CD180 |
Antibodies |
Anti-CD180 Antibody (CAB10226) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |