CBR4 Antibody (PACO45048)
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주문- SKU:
- PACO45048
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CBR4 Antibody (PACO45048) |
Antibody SKU: | PACO45048 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Carbonyl reductase family member 4 protein (1-237AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO45048 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO45048 at dilution of 1:100. |
Background: | The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acid, in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro). |
Synonyms: | Carbonyl reductase family member 4 (EC 1) (3-ketoacyl-[acyl-carrier-protein] reductase β subunit) (KAR β subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) (Quinone reductase CBR4) (Short chain dehydrogenase/reductase family 45C member 1), CBR4, SDR45C1 |
UniProt Protein Function: | CBR4: The heteroteramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 1.-.-.-; Oxidoreductase; Mitochondrial; EC 1.1.1.- Chromosomal Location of Human Ortholog: 4q32.3 Cellular Component: mitochondrial matrix Molecular Function:protein binding; NAD(P)H dehydrogenase (quinone) activity; NADPH dehydrogenase (quinone) activity; quinone binding Biological Process: fatty acid biosynthetic process; protein homotetramerization |
UniProt Code: | Q8N4T8 |
NCBI GenInfo Identifier: | 269849708 |
NCBI Gene ID: | 84869 |
NCBI Accession: | Q8N4T8.3 |
UniProt Secondary Accession: | Q8N4T8,Q8WTW8, Q96K93, |
UniProt Related Accession: | Q8N4T8 |
Molecular Weight: | 237 |
NCBI Full Name: | Carbonyl reductase family member 4 |
NCBI Synonym Full Names: | carbonyl reductase 4 |
NCBI Official Symbol: | CBR4 |
NCBI Official Synonym Symbols: | SDR45C1 |
NCBI Protein Information: | carbonyl reductase family member 4; carbonic reductase 4; quinone reductase CBR4; 3-oxoacyl-[acyl-carrier-protein] reductase; short chain dehydrogenase/reductase family 45C, member 1 |
UniProt Protein Name: | Carbonyl reductase family member 4 |
UniProt Synonym Protein Names: | 3-oxoacyl-[acyl-carrier-protein] reductase (EC:1.1.1.-); Quinone reductase CBR4 |
Protein Family: | Carbonyl reductase family |
UniProt Gene Name: | CBR4 |
UniProt Entry Name: | CBR4_HUMAN |