CALB1 Antibody (PACO15905)
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주문- SKU:
- PACO15905
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CALB1 Antibody (PACO15905) |
Antibody SKU: | PACO15905 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human CALB1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse brain tissue, Mouse kidney tissue, human fetal brain tissue, Primary antibody: PACO15905(CALB1 Antibody) at dilution 1/750, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15905(CALB1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted. |
Synonyms: | calbindin 1, 28kDa |
UniProt Protein Function: | CALB1: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. Interacts with RANBP9. Belongs to the calbindin family. |
UniProt Protein Details: | Protein type:Calcium-binding Chromosomal Location of Human Ortholog: 8q21.3 Cellular Component: cell soma; axon; dendrite; synapse; nucleus; cytosol Molecular Function:vitamin D binding; protein binding; zinc ion binding; calcium ion binding Biological Process: cytosolic calcium ion homeostasis; long-term memory; short-term memory; regulation of synaptic plasticity; locomotory behavior |
NCBI Summary: | Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted. [provided by RefSeq, Jul 2008] |
UniProt Code: | P05937 |
NCBI GenInfo Identifier: | 115394 |
NCBI Gene ID: | 793 |
NCBI Accession: | P05937.2 |
UniProt Secondary Accession: | P05937,B2R696, B7Z9J4, |
UniProt Related Accession: | P05937 |
Molecular Weight: | 23,609 Da |
NCBI Full Name: | Calbindin |
NCBI Synonym Full Names: | calbindin 1, 28kDa |
NCBI Official Symbol: | CALB1 |
NCBI Official Synonym Symbols: | CALB |
NCBI Protein Information: | calbindin; D-28K; calbindin D28; RTVL-H protein; calbindin 1, (28kD); vitamin D-dependent calcium-binding protein, avian-type |
UniProt Protein Name: | Calbindin |
UniProt Synonym Protein Names: | Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein, avian-type |
Protein Family: | Calbindin |
UniProt Gene Name: | CALB1 |
UniProt Entry Name: | CALB1_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |