CADM3 Antibody (PACO15903)
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주문- SKU:
- PACO15903
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CADM3 Antibody (PACO15903) |
Antibody SKU: | PACO15903 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human CADM3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO15903(CADM3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO15903(CADM3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Cell adhesion molecule 3 is a protein that in humans is encoded by the CADM3 gene. IGSF4B is a brain-specific protein related to the calcium-independent cell-cell adhesion molecules known as nectins. Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions. |
Synonyms: | cell adhesion molecule 3 |
UniProt Protein Function: | CADM3: Involved in the cell-cell adhesion. Has both calcium- independent homophilic cell-cell adhesion activity and calcium- independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions. Belongs to the nectin family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 1q21.2-q22 Cellular Component: cell-cell adherens junction; integral to plasma membrane; intercellular junction; plasma membrane Molecular Function:cell adhesion molecule binding; protein homodimerization activity; receptor activity; receptor binding Biological Process: cell recognition; heterophilic cell adhesion; homophilic cell adhesion; intercellular junction assembly and maintenance; protein localization |
NCBI Summary: | IGSF4B is a brain-specific protein related to the calcium-independent cell-cell adhesion molecules known as nectins (see PVRL3; MIM 607147) (Kakunaga et al., 2005 [PubMed 15741237]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q8N126 |
NCBI GenInfo Identifier: | 74759761 |
NCBI Gene ID: | 57863 |
NCBI Accession: | Q8N126.1 |
UniProt Secondary Accession: | Q8N126,Q8IZQ9, Q9NVJ5, Q9UJP1, |
UniProt Related Accession: | Q8N126 |
Molecular Weight: | 38,326 Da |
NCBI Full Name: | Cell adhesion molecule 3 |
NCBI Synonym Full Names: | cell adhesion molecule 3 |
NCBI Official Symbol: | CADM3 |
NCBI Official Synonym Symbols: | BIgR; NECL1; TSLL1; IGSF4B; Necl-1; synCAM3 |
NCBI Protein Information: | cell adhesion molecule 3 |
UniProt Protein Name: | Cell adhesion molecule 3 |
UniProt Synonym Protein Names: | Brain immunoglobulin receptor; Immunoglobulin superfamily member 4B; IgSF4B; Nectin-like protein 1; NECL-1; Synaptic cell adhesion molecule 3; SynCAM3; TSLC1-like protein 1; TSLL1 |
Protein Family: | Cell adhesion molecule |
UniProt Gene Name: | CADM3 |
UniProt Entry Name: | CADM3_HUMAN |
Antibodies | ELISA Kits |
Anti-CADM3 Antibody (CAB4902) | Human CADM3 / NECL-1 ELISA Kit |
CADM3 Antibody (PACO03049) | Human Cell adhesion molecule 3 (CADM3) ELISA Kit |
CADM3 Antibody (PACO08140) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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