CAB39 Antibody (PACO62755)
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주문- SKU:
- PACO62755
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CAB39 Antibody (PACO62755) |
Antibody SKU: | PACO62755 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Calcium-binding protein 39 protein (28-290AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescence staining of Hela cells with PACO62755 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25α or CAB39L/MO25beta) and STK11/LKB1. |
Synonyms: | Calcium-binding protein 39 (MO25alpha) (Protein Mo25), CAB39, MO25 |
UniProt Protein Function: | CAB39: a adaptor protein that, together with STRAD-alpha, forms a regulatory complex capable of stimulating the activity of LKB1. Interacts with Mst4, which plays an essential role in brush border formation in intestinal epithelial cells. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 2q37.1 Cellular Component: cytosol Molecular Function:protein serine/threonine kinase activator activity; protein serine/threonine kinase activity; protein binding; kinase binding; protein kinase activator activity Biological Process: protein heterooligomerization; activation of protein kinase activity; insulin receptor signaling pathway; cell cycle arrest; protein amino acid phosphorylation; positive regulation of peptidyl-serine phosphorylation |
UniProt Code: | Q9Y376 |
NCBI GenInfo Identifier: | 195927020 |
NCBI Gene ID: | 51719 |
NCBI Accession: | NP_001124321.1 |
UniProt Secondary Accession: | Q9Y376,A8K8L7, |
UniProt Related Accession: | Q9Y376 |
Molecular Weight: | 39,869 Da |
NCBI Full Name: | calcium-binding protein 39 |
NCBI Synonym Full Names: | calcium binding protein 39 |
NCBI Official Symbol: | CAB39 |
NCBI Official Synonym Symbols: | MO25; CGI-66 |
NCBI Protein Information: | calcium-binding protein 39; MO25alpha |
UniProt Protein Name: | Calcium-binding protein 39 |
UniProt Synonym Protein Names: | MO25alpha; Protein Mo25 |
Protein Family: | Mo25-like protein |
UniProt Gene Name: | CAB39 |
UniProt Entry Name: | CAB39_HUMAN |
Antibodies |
Anti-CAB39 Antibody (CAB16125) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |