BOK Antibody (PACO18633)
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주문- SKU:
- PACO18633
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | BOK Antibody (PACO18633) |
Antibody SKU: | PACO18633 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:20-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human BOK(BH3 domain) |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO18633(BOK(BH3 domain) Antibody) at dilution 1/20, on the right is treated with synthetic peptide. | |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO18633(BOK(BH3 domain) Antibody) at dilution 1/20, on the right is treated with synthetic peptide. |
Background: | The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family. |
Synonyms: | BCL2-related ovarian killer |
UniProt Protein Function: | BOK: May play a role in apoptosis. Belongs to the Bcl-2 family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2q37.3 Cellular Component: cytoplasm; mitochondrial membrane; mitochondrial outer membrane; mitochondrion; nucleus Molecular Function:protein binding; protein heterodimerization activity; protein homodimerization activity Biological Process: apoptosis; caspase activation; cell proliferation; DNA damage response, signal transduction resulting in induction of apoptosis |
NCBI Summary: | The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family. [provided by RefSeq, Sep 2011] |
UniProt Code: | Q9UMX3 |
NCBI GenInfo Identifier: | 57012554 |
NCBI Gene ID: | 666 |
NCBI Accession: | Q9UMX3.1 |
UniProt Related Accession: | Q9UMX3 |
Molecular Weight: | 23,280 Da |
NCBI Full Name: | Bcl-2-related ovarian killer protein |
NCBI Synonym Full Names: | BOK, BCL2 family apoptosis regulator |
NCBI Official Symbol: | BOK |
NCBI Official Synonym Symbols: | BOKL; BCL2L9 |
NCBI Protein Information: | bcl-2-related ovarian killer protein |
UniProt Protein Name: | Bcl-2-related ovarian killer protein |
UniProt Synonym Protein Names: | Bcl-2-like protein 9; Bcl2-L-9 |
Protein Family: | Bcl-2-related ovarian killer protein |
UniProt Gene Name: | BOK |
UniProt Entry Name: | BOK_HUMAN |
Antibodies |
Anti-BOK Antibody (CAB16354) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |