BANP Antibody (PACO43428)
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주문- SKU:
- PACO43428
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | BANP Antibody (PACO43428) |
Antibody SKU: | PACO43428 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Protein BANP protein (1-260AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: BANP antibody at 6µg/ml + HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 57, 52, 49, 54, 55, 51, 56 kDa. Observed band size: 49 kDa. | |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO43428 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human breast cancer using PACO43428 at dilution of 1:100. |
Background: | Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) β enhancer function. Binds to scaffold/matrix attachment region β (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR β enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest. |
Synonyms: | Protein BANP (BEN domain-containing protein 1) (Btg3-associated nuclear protein) (Scaffold/matrix-associated region-1-binding protein), BANP, BEND1 SMAR1 |
UniProt Protein Function: | BANP: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest. Belongs to the BANP/SMAR1 family. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Tumor suppressor Chromosomal Location of Human Ortholog: 16q24 Cellular Component: nucleoplasm Molecular Function:protein binding; DNA binding; p53 binding Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development; chromatin modification; negative regulation of protein catabolic process; cell cycle |
NCBI Summary: | This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
UniProt Code: | Q8N9N5 |
NCBI GenInfo Identifier: | 308153628 |
NCBI Gene ID: | 54971 |
NCBI Accession: | Q8N9N5.3 |
UniProt Related Accession: | Q8N9N5 |
Molecular Weight: | |
NCBI Full Name: | Protein BANP |
NCBI Synonym Full Names: | BTG3 associated nuclear protein |
NCBI Official Symbol: | BANP |
NCBI Official Synonym Symbols: | BEND1; SMAR1; SMARBP1 |
NCBI Protein Information: | protein BANP |
UniProt Protein Name: | Protein BANP |
UniProt Synonym Protein Names: | BEN domain-containing protein 1; Btg3-associated nuclear protein; Scaffold/matrix-associated region-1-binding protein |
Protein Family: | Protein |
UniProt Gene Name: | BANP |
UniProt Entry Name: | BANP_HUMAN |
Antibodies | ELISA Kits |
Anti-BANP Antibody (CAB7595) | Human BANP / BTG3 Associated Nuclear Protein ELISA Kit |
BANP Antibody (PACO07978) | Human BANP (BTG3 Associated Nuclear Protein) CLIA Kit (HUES01269) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |