B3GALT4 Antibody (PACO51346)
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주문- SKU:
- PACO51346
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | B3GALT4 Antibody (PACO51346) |
Antibody SKU: | PACO51346 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Beta-1,3-galactosyltransferase 4 protein (42-266AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: U87 whole cell lysate, A549 whole cell lysate, Mouse skeletal muscle tissue. All lanes: B3GALT4 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 42 kDa. Observed band size: 42 kDa.. | |
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO51346 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human lung cancer using PACO51346 at dilution of 1:100. |
Background: | Involved in GM1/GD1B/GA1 ganglioside biosynthesis. |
Synonyms: | Beta-1,3-galactosyltransferase 4 (Beta-1,3-GalTase 4) (Beta3Gal-T4) (Beta3GalT4) (GalT4) (b3Gal-T4) (EC 2.4.1.62) (Gal-T2) (Ganglioside galactosyltransferase) (UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase), B3GALT4, GALT4 |
UniProt Protein Function: | B3GALT4: Involved in GM1/GD1B/GA1 ganglioside biosynthesis. Belongs to the glycosyltransferase 31 family. |
UniProt Protein Details: | Protein type:EC 2.4.1.62; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Membrane protein, integral; Transferase Chromosomal Location of Human Ortholog: 6p21.32 Molecular Function:UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity |
NCBI Summary: | This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis. [provided by RefSeq, Jul 2008] |
UniProt Code: | O96024 |
NCBI GenInfo Identifier: | 4502341 |
NCBI Gene ID: | 8705 |
NCBI Accession: | NP_003773.1 |
UniProt Related Accession: | O96024 |
Molecular Weight: | 41.5 |
NCBI Full Name: | beta-1,3-galactosyltransferase 4 |
NCBI Synonym Full Names: | beta-1,3-galactosyltransferase 4 |
NCBI Official Symbol: | B3GALT4 |
NCBI Official Synonym Symbols: | GALT2; GALT4; BETA3GALT4 |
NCBI Protein Information: | beta-1,3-galactosyltransferase 4 |
UniProt Protein Name: | Beta-1,3-galactosyltransferase 4 |
UniProt Synonym Protein Names: | Gal-T2; Ganglioside galactosyltransferase; UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase |
Protein Family: | Beta-1,3-galactosyltransferase |
UniProt Gene Name: | B3GALT4 |