ATP7A Antibody (PACO19330)
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주문- SKU:
- PACO19330
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ATP7A Antibody (PACO19330) |
Antibody SKU: | PACO19330 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human ATP7A |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO19330(ATP7A Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19330(ATP7A Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. |
Synonyms: | ATPase, Cu++ transporting, α polypeptide |
UniProt Protein Function: | May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells. |
NCBI Summary: | This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q04656 |
NCBI GenInfo Identifier: | 223590241 |
NCBI Gene ID: | 538 |
NCBI Accession: | Q04656.3 |
UniProt Secondary Accession: | Q04656,O00227, O00745, Q9BYY8, B1AT72, |
UniProt Related Accession: | Q04656 |
Molecular Weight: | 11,522 Da |
NCBI Full Name: | Copper-transporting ATPase 1 |
NCBI Synonym Full Names: | ATPase copper transporting alpha |
NCBI Official Symbol: | ATP7A |
NCBI Official Synonym Symbols: | MK; MNK; DSMAX; SMAX3 |
NCBI Protein Information: | copper-transporting ATPase 1 |
UniProt Protein Name: | Copper-transporting ATPase 1 |
UniProt Synonym Protein Names: | Copper pump 1; Menkes disease-associated protein |
UniProt Gene Name: | ATP7A |
UniProt Entry Name: | ATP7A_HUMAN |
Antibodies | ELISA Kits |
Anti-ATP7A Antibody (CAB8399) | Human ATP7A / Copper-transporting ATPase 1 ELISA Kit |
ATP7A Antibody (PACO04618) | Human Copper-transporting ATPase 1 (ATP7A) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |