ARHGAP25 Antibody (PACO15508)
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주문- SKU:
- PACO15508
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ARHGAP25 Antibody (PACO15508) |
Antibody SKU: | PACO15508 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human ARHGAP25 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15508(ARHGAP25 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: PACO15508(ARHGAP25 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15508(ARHGAP25 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Rho GTPase activating protein 25 is a protein that in humans is encoded by the ARHGAP25 gene. The gene is also known as KAIA0053. ARHGAP25 belongs to a family of Rho GTPase-modulating proteins which are implicated in actin remodeling, cell polarity, and cell migration. GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. |
Synonyms: | Rho GTPase activating protein 25 |
UniProt Protein Function: | ARHGAP25: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:GAPs, Rac/Rho; GAPs Chromosomal Location of Human Ortholog: 2p13.3 Cellular Component: cytosol Molecular Function:GTPase activator activity Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of GTPase activity |
NCBI Summary: | ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).[supplied by OMIM, Mar 2008] |
UniProt Code: | P42331 |
NCBI GenInfo Identifier: | 238054314 |
NCBI Gene ID: | 9938 |
NCBI Accession: | P42331.2 |
UniProt Secondary Accession: | P42331,Q8IXQ2, A8K2Y1, B7Z498, E9PFQ7, G5E9G2, |
UniProt Related Accession: | P42331 |
Molecular Weight: | 645 |
NCBI Full Name: | Rho GTPase-activating protein 25 |
NCBI Synonym Full Names: | Rho GTPase activating protein 25 |
NCBI Official Symbol: | ARHGAP25 |
NCBI Official Synonym Symbols: | KAIA0053; HEL-S-308 |
NCBI Protein Information: | rho GTPase-activating protein 25; epididymis secretory protein Li 308; rho-type GTPase-activating protein 25 |
UniProt Protein Name: | Rho GTPase-activating protein 25 |
UniProt Synonym Protein Names: | Rho-type GTPase-activating protein 25 |
UniProt Gene Name: | ARHGAP25 |
UniProt Entry Name: | RHG25_HUMAN |
Antibodies |
Anti-ARHGAP25 Antibody (CAB1223) |
Anti-ARHGAP25 Antibody (CAB13664) |
ARHGAP25 Antibody (PACO07823) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |