ARG1 Antibody (PACO51322)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO51322
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ARG1 Antibody (PACO51322) |
Antibody SKU: | PACO51322 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Recombinant Human Arginase-1 protein (1-322AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Mouse liver tissue, Rat liver tissue. All lanes: ARG1 antibody at 2.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 35, 36, 26 kDa. Observed band size: 35 kDa.. | |
Immunohistochemistry of paraffin-embedded human liver tissue using PACO51322 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO51322 at dilution of 1:100. |
Background: | cytoplasm, cytosol, extracellular exosome, nucleus, arginase activity, arginine catabolic process, urea cycle |
Synonyms: | Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase), ARG1 |
UniProt Protein Function: | ARG1: Homotrimer. By arginine or homoarginine. Belongs to the arginase family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Amino Acid Metabolism - arginine and proline; EC 3.5.3.1; Hydrolase Chromosomal Location of Human Ortholog: 6q23.2 Cellular Component: cytoplasm; cytosol; extracellular region; nucleus Molecular Function:arginase activity Biological Process: arginine catabolic process; neutrophil degranulation; urea cycle Disease: Argininemia |
NCBI Summary: | Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
UniProt Code: | P05089 |
NCBI GenInfo Identifier: | 12230985 |
NCBI Gene ID: | 383 |
NCBI Accession: | P05089.2 |
UniProt Secondary Accession: | P05089,Q5JWT5, Q5JWT6, Q8TE72, Q9BS50, A6NEA0, |
UniProt Related Accession: | P05089 |
Molecular Weight: | 35kDa |
NCBI Full Name: | Arginase-1 |
NCBI Synonym Full Names: | arginase 1 |
NCBI Official Symbol: | ARG1 |
NCBI Protein Information: | arginase-1 |
UniProt Protein Name: | Arginase-1 |
UniProt Synonym Protein Names: | Liver-type arginase; Type I arginase |
Protein Family: | Arginase |
UniProt Gene Name: | ARG1 |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |