APOC1 Antibody (PACO15478)
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주문- SKU:
- PACO15478
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | APOC1 Antibody (PACO15478) |
Antibody SKU: | PACO15478 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human APOC1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal liver tissue, Primary antibody: PACO15478(APOC1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
Background: | The protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. |
Synonyms: | apolipoprotein C-I |
UniProt Protein Function: | APOC1: Appears to modulate the interaction of APOE with beta- migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification. Belongs to the apolipoprotein C1 family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Lipid-binding; Secreted; Inhibitor; Endoplasmic reticulum Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: chylomicron; endoplasmic reticulum Molecular Function:phospholipase inhibitor activity; lipase inhibitor activity; phosphatidylcholine binding; fatty acid binding Biological Process: positive regulation of catalytic activity; cholesterol metabolic process; triacylglycerol metabolic process; phospholipid efflux; negative regulation of lipid catabolic process; negative regulation of cholesterol transport; negative regulation of lipoprotein lipase activity; cholesterol efflux; lipoprotein metabolic process; negative regulation of receptor-mediated endocytosis; lipid metabolic process; negative regulation of lipid metabolic process; regulation of cholesterol transport; negative regulation of fatty acid biosynthetic process |
NCBI Summary: | The protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | P02654 |
NCBI GenInfo Identifier: | 114016 |
NCBI Gene ID: | 341 |
NCBI Accession: | P02654.1 |
UniProt Secondary Accession: | P02654,Q6IB97, B2R526, |
UniProt Related Accession: | P02654 |
Molecular Weight: | 83 |
NCBI Full Name: | Apolipoprotein C-I |
NCBI Synonym Full Names: | apolipoprotein C-I |
NCBI Official Symbol: | APOC1 |
NCBI Official Synonym Symbols: | Apo-CI; ApoC-I |
NCBI Protein Information: | apolipoprotein C-I; apo-CIB; apoC-IB; apolipoprotein C1; apolipoprotein C-I variant I |
UniProt Protein Name: | Apolipoprotein C-I |
UniProt Synonym Protein Names: | Apolipoprotein C1Truncated apolipoprotein C-I |
Protein Family: | Apolipoprotein |
UniProt Gene Name: | APOC1 |
UniProt Entry Name: | APOC1_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |