Anti-YTHDF2 Antibody (CAB15616)
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주문- SKU:
- CAB15616
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Antibody Name: | Anti-YTHDF2 Antibody |
Antibody SKU: | CAB15616 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human YTHDF2 (NP_057342.2). |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | 293T |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human YTHDF2 (NP_057342.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MSAS SLLE QRPK GQGN KVQN GSVH QKDG LNDD DFEP YLSP QARP NNAY TAMS DSYL PSYY SPSI GFSY SLGE AAWS TGGD TAMP YLTS YGQL SNGE PHFL PDAM FGQP GALG STPF LGQH GFNF FPSG IDFS AWGN NSSQ GQST QSSG YSSN YAYA PSSL GGAM IDGQ SAFA NETL NKAP GMNT IDQG MAAL KLGS TEVA |
Gene ID: | 51441 |
Uniprot: | Q9Y5A9 |
Cellular Location: | Cytoplasm, P-body |
Calculated MW: | 56kDa/62kDa |
Observed MW: | 62KDa |
Synonyms: | YTHDF2, CAHL, HGRG8, NY-REN-2 |
Background: | This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. |
UniProt Code: | Q9Y5A9 |
NCBI GenInfo Identifier: | 290543591 |
NCBI Gene ID: | 51441 |
NCBI Accession: | NP_001166299.1 |
UniProt Secondary Accession: | Q9Y5A9,Q5VSZ9, Q8TDH0, Q9BUJ5, A6NKG4, A8K966, B4E1G7 D3DPM8, |
UniProt Related Accession: | Q9Y5A9 |
Molecular Weight: | 62,334 Da |
NCBI Full Name: | YTH domain-containing family protein 2 isoform 2 |
NCBI Synonym Full Names: | YTH domain family, member 2 |
NCBI Official Symbol: | YTHDF2 |
NCBI Official Synonym Symbols: | HGRG8; NY-REN-2 |
NCBI Protein Information: | YTH domain-containing family protein 2; 9430020E02Rik; CLL-associated antigen KW-14; high-glucose-regulated protein 8; renal carcinoma antigen NY-REN-2 |
UniProt Protein Name: | YTH domain-containing family protein 2 |
UniProt Synonym Protein Names: | CLL-associated antigen KW-14; High-glucose-regulated protein 8; Renal carcinoma antigen NY-REN-2 |
UniProt Gene Name: | YTHDF2 |
UniProt Entry Name: | YTHD2_HUMAN |
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