Anti-USP28 Antibody (CAB10400)
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주문- SKU:
- CAB10400
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Antibody Name: | Anti-USP28 Antibody |
Antibody SKU: | CAB10400 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 430-580 of human USP28 (NP_065937.1). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse |
Positive Samples: | U-87MG, LO2, 293T, DU145, Mouse brain |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 430-580 of human USP28 (NP_065937.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | VKYG SGPA RFPL PDML KYVI EFAS TKPA SESC PPES DTHM TLPL SSVH CSVS DQTS KEST STES SSQD VEST FSSP EDSL PKSK PLTS SRSS MEMP SQPA PRTV TDEE INFV KTCL QRWR SEIE QDIQ DLKT CIAS TTQT IEQM YCDP LLR |
Gene ID: | 57646 |
Uniprot: | Q96RU2 |
Cellular Location: | Nucleus, nucleoplasm |
Calculated MW: | 66kDa/119kDa/122kDa |
Observed MW: | 110kDa |
Synonyms: | USP28 |
Background: | The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. |
UniProt Protein Function: | USP28: a peptidase of the C19 family. USP28 and FBXW7 regulate Myc protein stability in response to DNA damage. Two isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.4.19.12; Protease; Ubiquitin-specific protease Chromosomal Location of Human Ortholog: 11q23.2 Cellular Component: nuclear body; nucleoplasm; protein complex Molecular Function:protein binding; ubiquitin-specific protease activity Biological Process: cell proliferation; DNA damage checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; protein deubiquitination; Ras protein signal transduction; regulation of protein stability; response to DNA damage stimulus; response to ionizing radiation |
NCBI Summary: | The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016] |
UniProt Code: | Q96RU2 |
NCBI GenInfo Identifier: | 20140700 |
NCBI Gene ID: | 57646 |
NCBI Accession: | Q96RU2.1 |
UniProt Secondary Accession: | Q96RU2,Q6NZX9, Q9P213, B0YJC0, B0YJC1, |
UniProt Related Accession: | Q96RU2 |
Molecular Weight: | 122kDa |
NCBI Full Name: | Ubiquitin carboxyl-terminal hydrolase 28 |
NCBI Synonym Full Names: | ubiquitin specific peptidase 28 |
NCBI Official Symbol: | USP28 |
NCBI Protein Information: | ubiquitin carboxyl-terminal hydrolase 28 |
UniProt Protein Name: | Ubiquitin carboxyl-terminal hydrolase 28 |
UniProt Synonym Protein Names: | Deubiquitinating enzyme 28; Ubiquitin thioesterase 28; Ubiquitin-specific-processing protease 28 |
Protein Family: | Ubiquitin carboxyl-terminal hydrolase |
UniProt Gene Name: | USP28 |
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