Anti-SARS-COV-2 N Protein Antibody (CAB20016)
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주문- SKU:
- CAB20016
- Product type:
- Antibody
- Reactivity:
- SARS-CoV-2
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Antibody Name: | Anti-SARS-COV-2 N Protein Antibody |
Antibody SKU: | CAB20016 |
Antibody Size: | 50uL, 100uL |
Application: | WB IHC IF IP FC ELISA |
Reactivity: | SARS-CoV-2 |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein of SARS-COV-2 Nucleoprotein. |
Application: | WB IHC IF IP FC ELISA |
Recommended Dilution: | WB 1:1000 - 1:5000 ELISA 1:1000 - 1:5000 FCM 1:50 - 1:200 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200 |
Reactivity: | SARS-CoV-2 |
Positive Samples: |
Immunogen: | Recombinant fusion protein of SARS-COV-2 Nucleoprotein. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at 4?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 1489678 |
Uniprot: | P59595 |
Cellular Location: | |
Calculated MW: | |
Observed MW: |
Synonyms: | Nucleoprotein, NP |
Background: | Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
UniProt Protein Function: | Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. |
UniProt Code: | P59595 |
NCBI GenInfo Identifier: | 30173007 |
NCBI Gene ID: | 1489678 |
NCBI Accession: | P59595.1 |
UniProt Secondary Accession: | P59595,Q7T3Z4, Q7TA14, Q7TF99, Q80E50, |
UniProt Related Accession: | P59595 |
Molecular Weight: | 46,025 Da |
NCBI Full Name: | Nucleoprotein |
NCBI Official Symbol: | N |
NCBI Protein Information: | nucleocapsid protein |
UniProt Protein Name: | Nucleoprotein |
UniProt Synonym Protein Names: | Nucleocapsid protein; NC; Protein N |
UniProt Gene Name: | N |
UniProt Entry Name: | NCAP_CVHSA |