Anti-PGC1 alpha Antibody (CAB17089)
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주문- SKU:
- CAB17089
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Antibody Name: | Anti-PGC1 alpha Antibody |
Antibody SKU: | CAB17089 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of mouse PGC1 alpha (NP_032930.1). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | 293T, HepG2, Mouse spleen, Mouse liver, Mouse kidney, Rat kidney |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of mouse PGC1 alpha (NP_032930.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MAWD MCSQ DSVW SDIE CAAL VGED QPLC PDLP ELDL SELD VNDL DTDS FLGG LKWC SDQS EIIS NQYN NEPA NIFE KIDE ENEA NLLA VLTE TLDS LPVD EDGL PSFD ALTD GAVT TDNE ASPS SMPD GTPP PQEA EEPS LLKK LLLA PANT QLSY NECS GLST QNHA ANHT HRIR TNPA IVKT ENSW SNKA KSIC QQQK PQRR PCSE LLKY LTTN DDPP HTKP TENR NSSR DKCA SKKK SHTQ PQSQ HAQA KPTT LSLP LTPE SPND PKGS PFEN KTIE RTLS VELS GTAG LTPP TTPP |
Gene ID: | 19017 |
Uniprot: | O70343 |
Cellular Location: | |
Calculated MW: | 14kDa/30kDa/31kDa/33kDa/77kDa/89kDa/91kDa |
Observed MW: | 110kDa |
Synonyms: | PPARGC1A, LEM6, PGC-1(alpha), PGC-1alpha, PGC-1v, PGC1, PGC1A, PPARGC1, PPARG coactivator 1 alpha, PGC1 alpha, Ppargc1a |
Background: | The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. |
UniProt Code: | O70343 |
NCBI GenInfo Identifier: | |
NCBI Gene ID: | |
NCBI Accession: | |
UniProt Secondary Accession: | O70343,Q9UBK2, O70343, Q8VHJ7, Q811R2 Q9QYK2, |
Molecular Weight: | 113kDa |
NCBI Full Name: | |
UniProt Protein Name: | |
UniProt Gene Name: |
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