Anti-PGAM1 Antibody (RACO0515)
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주문- SKU:
- RACO0515
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- WB
- Application:
- ELISA
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Product Name: | PGAM1 Antibody |
Product SKU: | RACO0515 |
Size: | 50ul |
Host Species: | Homo sapiens (Human) |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:5000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | A synthesized peptide derived from human PGAM1 |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | Affinity-chromatography |
Clonality: | Monoclonal |
Isotype: | Rabbit IgG |
Conjugate: | Non-conjugated |
Background: | Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity. |
Synonyms: | Phosphoglycerate mutase 1 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B), PGAM1, PGAMA |
Western Blot. Positive WB detected in Hela whole cell lysate 293 whole cell lysate HepG2 whole cell lysate NIH/3T3 whole cell lysate A549 whole cell lysate MCF-7 whole cell lysate Mouse Brain whole cell lysate Rat Brain whole cell lysate All lanes PGAM1 Antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1:50000 dilution. Predicted band size: 28 kDa. Observed band size: 29 kDa. |
UniProt Protein Function: | PGAM1: Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. Homodimer. In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. |
UniProt Protein Details: | Protein type:EC 5.4.2.4; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Isomerase; EC 3.1.3.13; Phosphatase (non-protein); EC 5.4.2.11 Chromosomal Location of Human Ortholog: 10q25.3 Cellular Component: membrane; cytoplasm; cytosol Molecular Function:protein binding; phosphoglycerate mutase activity; bisphosphoglycerate mutase activity; bisphosphoglycerate phosphatase activity; protein kinase binding Biological Process: respiratory burst; glycolysis; dephosphorylation; regulation of glycolysis; carbohydrate metabolic process; glucose metabolic process; pathogenesis; regulation of pentose-phosphate shunt; gluconeogenesis |
NCBI Summary: | Phosphoglyceric acid mutase (EC 2.7.5.3) is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway (summary by Chen et al., 1974 [PubMed 4811757]).[supplied by OMIM, Nov 2010] |
UniProt Code: | P18669 |
NCBI GenInfo Identifier: | 130348 |
NCBI Gene ID: | 5223 |
NCBI Accession: | P18669.2 |
UniProt Secondary Accession: | P18669,Q9BWC0, |
UniProt Related Accession: | P18669 |
Molecular Weight: | 254 |
NCBI Full Name: | Phosphoglycerate mutase 1 |
NCBI Synonym Full Names: | phosphoglycerate mutase 1 (brain) |
NCBI Official Symbol: | PGAM1Â Â |
NCBI Official Synonym Symbols: | PGAMA; PGAM-B; HEL-S-35Â Â |
NCBI Protein Information: | phosphoglycerate mutase 1; BPG-dependent PGAM 1; phosphoglycerate mutase isozyme B; epididymis secretory protein Li 35; phosphoglycerate mutase A, nonmuscle form |
UniProt Protein Name: | Phosphoglycerate mutase 1 |
UniProt Synonym Protein Names: | BPG-dependent PGAM 1; Phosphoglycerate mutase isozyme B; PGAM-B |
Protein Family: | Phosphoglycerate mutase |
UniProt Gene Name: | PGAM1Â Â |
UniProt Entry Name: | PGAM1_HUMAN |