Anti-PD-1/CD279 Antibody (CAB20223)

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주문
SKU:
CAB20223
Product type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG
Synonyms:
PDCD1
Synonyms:
CD279
Synonyms:
PD-1
Synonyms:
PD1
Synonyms:
SLEB2
Synonyms:
hPD-1
Synonyms:
hPD-l
Synonyms:
hSLE1
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Description

Product Name:PD-1/CD279 Mouse mAb
Product Code:CAB20223
Size:50uL, 100uL
Synonyms:PDCD1, CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1
Applications:WB
Reactivity:Human
Host Species:Mouse
Immunogen:Recombinant protein of human PD-1/CD279.
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Immunogen:Recombinant protein of human PD-1/CD279.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% sodium azide, 0.2% BSA, 40% glycerol, pH7.4.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5133
Uniprot:Q15116
Cellular Location:Membrane, Single-pass type I membrane protein
Calculated MW:31kDa
Observed MW:Refer to figures
UniProt Protein Function:Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.
NCBI Summary:This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
UniProt Code:Q15116
NCBI GenInfo Identifier:145559515
NCBI Gene ID:5133
NCBI Accession:Q15116.3
UniProt Secondary Accession:Q15116,Q02242,
UniProt Related Accession:Q15116
Molecular Weight:
NCBI Full Name:Programmed cell death protein 1
NCBI Synonym Full Names:programmed cell death 1
NCBI Official Symbol:PDCD1  
NCBI Official Synonym Symbols:PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1  
NCBI Protein Information:programmed cell death protein 1
UniProt Protein Name:Programmed cell death protein 1
UniProt Synonym Protein Names:CD_antigen: CD279
UniProt Gene Name:PDCD1  
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