Anti-MTCH2 Antibody (CAB19922)[KO Validated]
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- CAB19922
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Antibody Name: | Anti-MTCH2 Antibody [KO Validated] |
Antibody SKU: | CAB19922 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC IF |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human MTCH2. |
Application: | WB IHC IF |
Recommended Dilution: | WB 1:1000 - 1:3000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse |
Positive Samples: | 293T |
Immunogen: | Recombinant protein of human MTCH2. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 23788 |
Uniprot: | Q9Y6C9 |
Cellular Location: | Mitochondrion inner membrane, Multi-pass membrane protein |
Calculated MW: | 33kDa |
Observed MW: | 33KDa |
Synonyms: | MTCH2, HSPC032, MIMP, SLC25A50 |
Background: | This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. |
UniProt Protein Function: | MTCH2: The substrate transported is not yet known. Induces mitochondrial depolarization. Belongs to the mitochondrial carrier family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial Chromosomal Location of Human Ortholog: 11p11.2 Cellular Component: membrane; mitochondrion; nucleus Biological Process: positive regulation of apoptosis |
NCBI Summary: | This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. [provided by RefSeq, Nov 2015] |
UniProt Code: | Q9Y6C9 |
NCBI GenInfo Identifier: | 67461088 |
NCBI Gene ID: | 23788 |
NCBI Accession: | Q9Y6C9.1 |
UniProt Secondary Accession: | Q9Y6C9,B2R7L8, |
UniProt Related Accession: | Q9Y6C9 |
Molecular Weight: | 33kDa |
NCBI Full Name: | Mitochondrial carrier homolog 2 |
NCBI Synonym Full Names: | mitochondrial carrier 2 |
NCBI Official Symbol: | MTCH2 |
NCBI Official Synonym Symbols: | MIMP; HSPC032; SLC25A50 |
NCBI Protein Information: | mitochondrial carrier homolog 2 |
UniProt Protein Name: | Mitochondrial carrier homolog 2 |
UniProt Synonym Protein Names: | Met-induced mitochondrial protein |
Protein Family: | Mitochondrial carrier |
UniProt Gene Name: | MTCH2 |