Anti-MAGT1 Antibody (CAB5039)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- CAB5039
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MAGT1
- Synonyms:
- IAP
- Synonyms:
- MRX95
- Synonyms:
- OST3B
- Synonyms:
- PRO0756
- Synonyms:
- XMEN
- Synonyms:
- bA217H1.1
Frequently bought together:
Description
| Product Name: | MAGT1 Rabbit pAb |
| Product Code: | CAB5039 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | MAGT1, IAP, MRX95, OST3B, PRO0756, XMEN, bA217H1.1 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-220 of human MAGT1 (NP_115497.4). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:1000 |
| Reactivity: | Human |
| Positive Samples: | U-251MG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-220 of human MAGT1 (NP_115497.4). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SAQR KKEM VLSE KVSQ LMEW TNKR PVIR MNGD KFRR LVKA PPRN YSVI VMFT ALQL HRQC VVCK QADE EFQI LANS WRYS SAFT NRIF FAMV DFDE GSDV FQML NMNS APTF INFP AKGK PKRG DTYE LQVR GFSA EQIA RWIA DRTD VNIR VIRP PNYA G |
| Gene ID: | 84061 |
| Uniprot: | Q9H0U3 |
| Cellular Location: | Cell membrane, Endoplasmic reticulum membrane, Multi-pass membrane protein |
| Calculated MW: | 15kDa/38kDa |
| Observed MW: | 50kDa |
| UniProt Protein Function: | MAGT1: May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells. Defects in MAGT1 are the cause of mental retardation X- linked type 95 (MRX95). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. In contrast to syndromic or specific X-linked mental retardation which also present with associated physical, neurological and/or psychiatric manifestations, intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation. Defects in MAGT1 are the cause of immunodeficiency X- linked with magnesium defect Epstein-Barr virus infection and neoplasia (XMEN). XMEN is a disease characterized by CD4 lymphopenia, severe chronic viral infections, and defective T- lymphocyte activation. Belongs to the OST3/OST6 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: Xq21.1 Cellular Component: membrane; oligosaccharyl transferase complex; plasma membrane Molecular Function:magnesium ion transmembrane transporter activity Biological Process: cognition; magnesium ion transport; protein amino acid N-linked glycosylation via asparagine; transmembrane transport Disease: Immunodeficiency, X-linked, With Magnesium Defect, Epstein-barr Virus Infection, And Neoplasia |
| NCBI Summary: | This gene encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29. [provided by RefSeq, Jan 2010] |
| UniProt Code: | Q9H0U3 |
| NCBI GenInfo Identifier: | 74761391 |
| NCBI Gene ID: | 84061 |
| NCBI Accession: | Q9H0U3.1 |
| UniProt Secondary Accession: | Q9H0U3,Q53G00, Q6P577, Q8NBN6, B2RAR4, D3DTE3, |
| UniProt Related Accession: | Q9H0U3 |
| Molecular Weight: | 15,699 Da |
| NCBI Full Name: | Magnesium transporter protein 1 |
| NCBI Synonym Full Names: | magnesium transporter 1 |
| NCBI Official Symbol: | MAGT1 |
| NCBI Official Synonym Symbols: | IAP; XMEN; MRX95; OST3B; PRO0756; bA217H1.1 |
| NCBI Protein Information: | magnesium transporter protein 1 |
| UniProt Protein Name: | Magnesium transporter protein 1 |
| UniProt Synonym Protein Names: | Implantation-associated protein; IAP |
| Protein Family: | Magnesium transporter protein |
| UniProt Gene Name: | MAGT1 |
| UniProt Entry Name: | MAGT1_HUMAN |
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