Anti-IGFBP1 Antibody (MACO0574)
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주문- SKU:
- MACO0574
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Mouse
- Isotype:
- IgG1
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Monoclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Product Name: | Anti-IGFBP1 Antibody |
Product Sku: | MACO0574 |
Size: | 50ug |
Host Species: | Mouse |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:5000 |
Species Reactivity: | Human,Mouse |
Immunogen: | Recombinant Human IGFBP1 Protein |
Form: | Liquid |
Storage Buffer: | Preservative: 15mmol/L NaN3 Constituents: 0.1mol/L Nacl |
Purification Method: | >95%,Protein G purified |
Clonality: | Monoclonal |
Isotype: | IgG1 |
Conjugate: | Non-conjugated |
Background: | This gene is a member of the Insulin-like growth factor-binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a type-I thyroglobulin domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Synonyms: | IGFBP1,Insulin-like growth factor-binding protein 1,IGF-binding protein 1 |
All lanes: Mouse anti- Human Insulin-like growth factor-binding protein 1 monoclonal antibody at 1ug/ml Lane 1:Pyrolysis liquid human placental tissue 7.5ug/ml Lane 2:Pyrolysis liquid human placental tissue 3.25ug/ml Lane 3:IGFBP1 transfected SF9 cell lysate Lane 4:human amniotic fluid Secondary Goat polyclonal to Mouse IgG at 1/5000 dilution Predicted band size : 28kd Observed band size : 35kd |
UniProt Protein Function: | IGFBP1: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 7p12.3 Cellular Component: extracellular region; extracellular space Molecular Function:insulin-like growth factor binding; insulin-like growth factor I binding; insulin-like growth factor II binding Biological Process: cellular protein metabolic process; insulin receptor signaling pathway; positive regulation of cell growth; regulation of insulin-like growth factor receptor signaling pathway; signal transduction; tissue regeneration; unfolded protein response |
NCBI Summary: | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008] |
UniProt Code: | P08833 |
NCBI GenInfo Identifier: | 124055 |
NCBI Gene ID: | 3484 |
NCBI Accession: | P08833.1 |
UniProt Secondary Accession: | P08833,Q8IYP5, A4D2F4, D3DVL9, |
UniProt Related Accession: | P08833 |
Molecular Weight: | 27,904 Da |
NCBI Full Name: | Insulin-like growth factor-binding protein 1 |
NCBI Synonym Full Names: | insulin like growth factor binding protein 1 |
NCBI Official Symbol: | IGFBP1Â Â |
NCBI Official Synonym Symbols: | AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1Â Â |
NCBI Protein Information: | insulin-like growth factor-binding protein 1 |
UniProt Protein Name: | Insulin-like growth factor-binding protein 1 |
UniProt Synonym Protein Names: | Placental protein 12; PP12 |
Protein Family: | Insulin-like growth factor-binding protein |
UniProt Gene Name: | IGFBP1Â Â |
UniProt Entry Name: | IBP1_HUMAN |