Anti-Histone H2B Antibody (MACO0119)
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주문- SKU:
- MACO0119
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Mouse
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Monoclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Product Name: | Anti-Histone H2B Antibody |
Product Sku: | MACO0119 |
Size: | 50ug |
Host Species: | Mouse |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:5000 |
Species Reactivity: | Human,Mouse,Rat |
Immunogen: | Synthetic Peptide |
Form: | Liquid |
Storage Buffer: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
Purification Method: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Clonality: | Monoclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | |
Synonyms: | HIST1H2BB; H2BFF; Histone H2B type 1-B; Histone H2B.1; Histone H2B.f; H2B/f |
Western blot analysis of 1) Hela, 2) 3T3, 3) Raw264.7, 4) Rat Brain, 5) Rat Kidney, diluted at 1:2000. |
UniProt Protein Function: | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
NCBI Summary: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015] |
UniProt Code: | P33778 |
NCBI GenInfo Identifier: | 462236 |
NCBI Gene ID: | 3018 |
NCBI Accession: | P33778.2 |
UniProt Secondary Accession: | P33778,Q4KN36, |
UniProt Related Accession: | P33778 |
Molecular Weight: | 13,950 Da |
NCBI Full Name: | Histone H2B type 1-B |
NCBI Synonym Full Names: | histone cluster 1 H2B family member b |
NCBI Official Symbol: | HIST1H2BBÂ Â |
NCBI Official Synonym Symbols: | H2B.1; H2B/f; H2BFFÂ Â |
NCBI Protein Information: | histone H2B type 1-B |
UniProt Protein Name: | Histone H2B type 1-B |
UniProt Synonym Protein Names: | Histone H2B.1; Histone H2B.f; H2B/f |
Protein Family: | Histone |
UniProt Gene Name: | HIST1H2BBÂ Â |