Anti-CD1A Antibody (CAB5722)
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주문- SKU:
- CAB5722
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Antibody Name: | Anti-CD1A Antibody |
Antibody SKU: | CAB5722 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-181 of human CD1A (NP_001754.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | 293T, HepG2, BT-474 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-181 of human CD1A (NP_001754.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | LKEP LSFH VTWI ASFY NHSW KQNL VSGW LSDL QTHT WDSN SSTI VFLC PWSR GNFS NEEW KELE TLFR IRTI RSFE GIRR YAHE LQFE YPFE IQVT GGCE LHSG KVSG SFLQ LAYQ GSDF VSFQ NNSW LPYP VAGN MAKH FCKV LNQN QHEN DITH NLLS D |
Gene ID: | 909 |
Uniprot: | P06126 |
Cellular Location: | Cell membrane, Endosome membrane, Single-pass type I membrane protein |
Calculated MW: | 37kDa |
Observed MW: | 65kDa |
Synonyms: | CD1A, CD1, FCB6, HTA1, R4, T6 |
Background: | This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. |
NCBI Summary: | This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
UniProt Code: | P06126 |
NCBI GenInfo Identifier: | 288558852 |
NCBI Gene ID: | 909 |
NCBI Accession: | P06126.4 |
UniProt Related Accession: | P06126 |
Molecular Weight: | |
NCBI Full Name: | T-cell surface glycoprotein CD1a |
NCBI Synonym Full Names: | CD1a molecule |
NCBI Official Symbol: | CD1A |
NCBI Official Synonym Symbols: | R4; T6; CD1; FCB6; HTA1 |
NCBI Protein Information: | T-cell surface glycoprotein CD1a |
UniProt Protein Name: | T-cell surface glycoprotein CD1a |
UniProt Synonym Protein Names: | T-cell surface antigen T6/Leu-6; hTa1 thymocyte antigen; CD_antigen: CD1a |
Protein Family: | CD109 antigen |
UniProt Gene Name: | CD1A |
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