AMZ2 Antibody (PACO15497)
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주문- SKU:
- PACO15497
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AMZ2 Antibody (PACO15497) |
Antibody SKU: | PACO15497 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human AMZ2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15497(AMZ2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO15497(AMZ2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid, protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis. AMZ2 is also expressed in kidney, liver, pancreas, lung, brain and placenta, and in fetal tissues such as kidney, liver, lung and brain. AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. AMZ2 is inhibited by both general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin. |
Synonyms: | archaelysin family metallopeptidase 2 |
UniProt Protein Function: | AMZ2: Zinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze either neurogranin or angiotensin-2. Belongs to the peptidase M54 family. |
UniProt Protein Details: | Protein type:Protease; EC 3.-.-.- Chromosomal Location of Human Ortholog: 17q24.2 Molecular Function:metallopeptidase activity; zinc ion binding Biological Process: proteolysis |
UniProt Code: | Q86W34 |
NCBI GenInfo Identifier: | 317373321 |
NCBI Gene ID: | 51321 |
NCBI Accession: | Q86W34.2 |
UniProt Secondary Accession: | Q86W34,Q5XKF1, Q9NZE2, A6NLD9, B3KR44, |
UniProt Related Accession: | Q86W34 |
Molecular Weight: | 34,595 Da |
NCBI Full Name: | Archaemetzincin-2 |
NCBI Synonym Full Names: | archaelysin family metallopeptidase 2 |
NCBI Official Symbol: | AMZ2 |
NCBI Protein Information: | archaemetzincin-2; archaemetzincins-2; archeobacterial metalloproteinase-like protein 2 |
UniProt Protein Name: | Archaemetzincin-2 |
UniProt Synonym Protein Names: | Archeobacterial metalloproteinase-like protein 2 |
Protein Family: | Archaemetzincin |
UniProt Gene Name: | AMZ2 |
UniProt Entry Name: | AMZ2_HUMAN |