AMPH Antibody (PACO14022)
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주문- SKU:
- PACO14022
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AMPH Antibody (PACO14022) |
Antibody SKU: | PACO14022 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human AMPH |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO14022(AMPH Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 60 μg, Lane: Mouse lung tissue, Primary antibody: PACO14022(AMPH Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO14022(AMPH Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11. |
Synonyms: | amphiphysin |
UniProt Protein Function: | amphiphysin: May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 7p14-p13 Cellular Component: synaptic vesicle; synaptic vesicle membrane; cell junction; actin cytoskeleton Molecular Function:protein binding; phospholipid binding Biological Process: synaptic transmission; synaptic vesicle endocytosis; endocytosis; learning |
NCBI Summary: | This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Nov 2010] |
UniProt Code: | P49418 |
NCBI GenInfo Identifier: | 1351924 |
NCBI Gene ID: | 273 |
NCBI Accession: | P49418.1 |
UniProt Secondary Accession: | P49418,O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0, A4D1X8 A4D1X9, |
UniProt Related Accession: | P49418 |
Molecular Weight: | 695 |
NCBI Full Name: | Amphiphysin |
NCBI Synonym Full Names: | amphiphysin |
NCBI Official Symbol: | AMPH |
NCBI Official Synonym Symbols: | AMPH1 |
NCBI Protein Information: | amphiphysin; amphiphysin I; amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen) |
UniProt Protein Name: | Amphiphysin |
Protein Family: | Amphinase |
UniProt Gene Name: | AMPH |
UniProt Entry Name: | AMPH_HUMAN |
Antibodies | ELISA Kits |
Anti-AMPH Antibody (CAB5389) | Human AMPH / Anti-Amphiphysin ELISA Kit |
AMPH Antibody (PACO07055) | |
AMPH Antibody (PACO07721) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |