ALCAM Antibody (PACO02082)
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주문- SKU:
- PACO02082
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ALCAM Antibody |
Antibody SKU: | PACO02082 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from the C-terminal region of human CD166. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | ALCAM; MEMD; CD166 antigen; Activated leukocyte cell adhesion molecule; CD166 |
UniProt Protein Function: | ALCAM: Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 3q13.1 Cellular Component: focal adhesion; cell soma; axon; integral to membrane; external side of plasma membrane Molecular Function:protein binding; receptor binding Biological Process: axon guidance; motor axon guidance; signal transduction; cell adhesion |
NCBI Summary: | This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011] |
UniProt Code: | Q13740 |
NCBI GenInfo Identifier: | 118572629 |
NCBI Gene ID: | 214 |
NCBI Accession: | Q13740.2 |
UniProt Secondary Accession: | Q13740,O60892, Q1HGM8, Q1HGM9, Q6PEY4, Q6ZS95, B2RNS3 B4DTU0, |
UniProt Related Accession: | Q13740 |
Molecular Weight: | 33,878 Da |
NCBI Full Name: | CD166 antigen |
NCBI Synonym Full Names: | activated leukocyte cell adhesion molecule |
NCBI Official Symbol: | ALCAM |
NCBI Official Synonym Symbols: | MEMD; CD166 |
NCBI Protein Information: | CD166 antigen |
UniProt Protein Name: | CD166 antigen |
UniProt Synonym Protein Names: | Activated leukocyte cell adhesion molecule; CD_antigen: CD166 |
Protein Family: | CD166 antigen |
UniProt Gene Name: | ALCAM |
UniProt Entry Name: | CD166_HUMAN |