AKR1B10 Antibody (PACO15364)
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주문- SKU:
- PACO15364
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AKR1B10 Antibody (PACO15364) |
Antibody SKU: | PACO15364 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human AKR1B10 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO15364(AKR1B10 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: A549 cells, Primary antibody: PACO15364(AKR1B10 Antibody) at dilution 1/184, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15364(AKR1B10 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. |
Synonyms: | aldo-keto reductase family 1, member B10 (aldose reductase) |
UniProt Protein Function: | AKR1B10: Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. Belongs to the aldo/keto reductase family. |
UniProt Protein Details: | Protein type:Lipid Metabolism - linoleic acid; Oxidoreductase; EC 1.1.1.21; Carbohydrate Metabolism - butanoate; Carbohydrate Metabolism - fructose and mannose; EC 1.1.1.- Chromosomal Location of Human Ortholog: 7q33 Cellular Component: cytosol Molecular Function:aldo-keto reductase activity; geranylgeranyl reductase activity; indanol dehydrogenase activity; protein binding; retinal dehydrogenase activity Biological Process: aldehyde metabolic process; digestion; farnesol catabolic process; retinoid metabolic process; steroid metabolic process |
NCBI Summary: | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008] |
UniProt Code: | O60218 |
NCBI GenInfo Identifier: | 322510010 |
NCBI Gene ID: | 57016 |
NCBI Accession: | O60218.2 |
UniProt Secondary Accession: | O60218,O75890, Q6FHF3, Q8IWZ1, A4D1P1, |
UniProt Related Accession: | O60218 |
Molecular Weight: | 36,020 Da |
NCBI Full Name: | Aldo-keto reductase family 1 member B10 |
NCBI Synonym Full Names: | aldo-keto reductase family 1 member B10 |
NCBI Official Symbol: | AKR1B10 |
NCBI Official Synonym Symbols: | HIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12 |
NCBI Protein Information: | aldo-keto reductase family 1 member B10 |
UniProt Protein Name: | Aldo-keto reductase family 1 member B10 |
UniProt Synonym Protein Names: | ARL-1; Aldose reductase-like; Aldose reductase-related protein; ARP; hARP; Small intestine reductase; SI reductase |
Protein Family: | Aldo-keto reductase family |
UniProt Gene Name: | AKR1B10 |
UniProt Entry Name: | AK1BA_HUMAN |
Antibodies | ELISA Kits |
Anti-AKR1B10 Antibody (CAB7823) | Human Aldo-keto reductase family 1 member B10 / AKR1B10 ELISA Kit |
Human Aldo-keto reductase family 1 member B10 (AKR1B10) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |