AKAP8 Antibody (PACO18287)
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주문- SKU:
- PACO18287
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AKAP8 Antibody (PACO18287) |
Antibody SKU: | PACO18287 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human AKAP8 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human liver cancer tissue, Primary antibody: PACO18287(AKAP8 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO18287(AKAP8 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII α subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. |
Synonyms: | A kinase (PRKA) anchor protein 8 |
UniProt Protein Function: | AKAP8: Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II). Belongs to the AKAP95 family. |
UniProt Protein Details: | Protein type:Cell cycle regulation; RNA-binding; Mitochondrial; Adaptor/scaffold Chromosomal Location of Human Ortholog: 19p13.1 Cellular Component: nucleoplasm; Golgi apparatus; nuclear matrix; membrane; mitochondrion; condensed chromosome; female pronucleus; nucleus Molecular Function:zinc ion binding; double-stranded DNA binding Biological Process: mitosis; mitotic chromosome condensation; signal transduction |
NCBI Summary: | This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011] |
UniProt Code: | O43823 |
NCBI GenInfo Identifier: | 5902752 |
NCBI Gene ID: | 10270 |
NCBI Accession: | O43823.1 |
UniProt Related Accession: | O43823 |
Molecular Weight: | 692 |
NCBI Full Name: | A-kinase anchor protein 8 |
NCBI Synonym Full Names: | A kinase (PRKA) anchor protein 8 |
NCBI Official Symbol: | AKAP8 |
NCBI Official Synonym Symbols: | AKAP-8; AKAP95; AKAP 95; AKAP-95 |
NCBI Protein Information: | A-kinase anchor protein 8; A-kinase anchor protein, 95kDa |
UniProt Protein Name: | A-kinase anchor protein 8 |
UniProt Synonym Protein Names: | A-kinase anchor protein 95 kDa; AKAP 95 |
Protein Family: | A-kinase anchor protein |
UniProt Gene Name: | AKAP8 |
UniProt Entry Name: | AKAP8_HUMAN |
Antibodies | ELISA Kits |
Anti-AKAP8 Antibody (CAB17302) | AKAP8 Colorimetric Cell-Based ELISA |
Anti-AKAP8 Antibody (CAB3049) | |
AKAP8 Antibody (PACO06241) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |