AGO1 Antibody (PACO64135)
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주문- SKU:
- PACO64135
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AGO1 Antibody (PACO64135) |
Antibody SKU: | PACO64135 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | IHC:1:200-1:500 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Protein argonaute-1 protein (251-400AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO64135 diluted at 1:200 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. |
Background: | Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs). |
Synonyms: | Protein argonaute-1 (Argonaute1) (hAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99), AGO1, EIF2C1 |
UniProt Code: | Q9UL18 |
NCBI GenInfo Identifier: | 88984241 |
NCBI Gene ID: | 26523 |
NCBI Accession: | Q9UL18.3 |
UniProt Secondary Accession: | Q9UL18,Q5TA57, Q6P4S0, |
UniProt Related Accession: | Q9UL18 |
Molecular Weight: | 857 |
NCBI Full Name: | Protein argonaute-1 |
NCBI Synonym Full Names: | argonaute RISC catalytic component 1 |
NCBI Official Symbol: | AGO1 |
NCBI Official Synonym Symbols: | Q99; EIF2C; EIF2C1; GERP95 |
NCBI Protein Information: | protein argonaute-1; hAgo1; eIF2C 1; eIF-2C 1; argonaute1; argonaute 1; putative RNA-binding protein Q99; Golgi Endoplasmic Reticulum protein 95 kDa; eukaryotic translation initiation factor 2C, 1 |
UniProt Protein Name: | Protein argonaute-1 |
UniProt Synonym Protein Names: | Argonaute RISC catalytic component 1; Eukaryotic translation initiation factor 2C 1; eIF-2C 1; eIF2C 1; Putative RNA-binding protein Q99 |
Protein Family: | Protein argonaute |
UniProt Gene Name: | AGO1 |
UniProt Entry Name: | AGO1_HUMAN |