ADSS Antibody (PACO43514)
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주문- SKU:
- PACO43514
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ADSS Antibody (PACO43514) |
Antibody SKU: | PACO43514 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Adenylosuccinate synthetase isozyme 2 protein (1-280AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: Adenylosuccinate synthetase isozyme 2 antibody at 12µg/ml. Lane 1: Mouse skeletal muscle tissue. Lane 2: HepG2 whole cell lysate. Lane 3: K562 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 50 kDa. Observed band size: 50 kDa. | |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO43514 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human colon tissue using PACO43514 at dilution of 1:100. |
Background: | Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. |
Synonyms: | Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acid, c isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2), ADSS, ADSS2 |
UniProt Protein Function: | ADSS: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. Belongs to the adenylosuccinate synthetase family. |
UniProt Protein Details: | Protein type:EC 6.3.4.4; Nucleotide Metabolism - purine; Ligase; Amino Acid Metabolism - alanine, aspartate and glutamate Chromosomal Location of Human Ortholog: 1q44 Cellular Component: cytoplasm; plasma membrane; cytosol Molecular Function:protein binding; GTP binding; magnesium ion binding; phosphate binding; adenylosuccinate synthase activity Biological Process: AMP biosynthetic process; response to purine; purine ribonucleoside monophosphate biosynthetic process; nucleobase, nucleoside and nucleotide metabolic process; immune system process; IMP metabolic process; aspartate metabolic process; purine base metabolic process |
NCBI Summary: | This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Nov 2010] |
UniProt Code: | P30520 |
NCBI GenInfo Identifier: | 21264498 |
NCBI Gene ID: | 159 |
NCBI Accession: | P30520.3 |
UniProt Secondary Accession: | P30520,Q96EG7, B1AQM5, |
UniProt Related Accession: | P30520 |
Molecular Weight: | 456 |
NCBI Full Name: | Adenylosuccinate synthetase isozyme 2 |
NCBI Synonym Full Names: | adenylosuccinate synthase |
NCBI Official Symbol: | ADSS |
NCBI Official Synonym Symbols: | ADEH; ADSS 2 |
NCBI Protein Information: | adenylosuccinate synthetase isozyme 2; adSS 2; AMPSase 2; IMP--aspartate ligase 2; L-type adenylosuccinate synthetase; adenylosuccinate synthetase, liver isozyme; adenylosuccinate synthetase, acidic isozyme; adenylosuccinate synthetase (Ade(-)H-complementing) |
UniProt Protein Name: | Adenylosuccinate synthetase isozyme 2 |
UniProt Synonym Protein Names: | Adenylosuccinate synthetase, acidic isozyme; Adenylosuccinate synthetase, liver isozyme; IMP--aspartate ligase 2 |
Protein Family: | Adenylosuccinate synthetase |
UniProt Gene Name: | ADSS |
UniProt Entry Name: | PURA2_HUMAN |