ADPGK Antibody (PACO44603)
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주문- SKU:
- PACO44603
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ADPGK Antibody (PACO44603) |
Antibody SKU: | PACO44603 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human ADP-dependent glucokinase protein (218-497AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: ADPGK antibody at 1.02µg/ml + Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 55, 54, 29, 25, 39, 9 kDa. Observed band size: 55 kDa.. | |
Immunohistochemistry of paraffin-embedded human liver tissue using PACO44603 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO44603 at dilution of 1:100. |
Background: | Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity). |
Synonyms: | ADP-dependent glucokinase (ADP-GK) (ADPGK) (EC 2.7.1.147) (RbBP-35), ADPGK |
UniProt Protein Function: | ADPGK: Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency. Belongs to the ADP-dependent glucokinase family. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 2.7.1.147; Secreted, signal peptide; Kinase, other; Secreted Chromosomal Location of Human Ortholog: 15q24.1 Cellular Component: membrane; extracellular region Molecular Function:ADP-specific glucokinase activity; metal ion binding Biological Process: glycolysis; phosphorylation |
NCBI Summary: | ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9BRR6 |
NCBI GenInfo Identifier: | 62899887 |
NCBI Gene ID: | 83440 |
NCBI Accession: | Q9BRR6.1 |
UniProt Secondary Accession: | Q9BRR6,Q49AU7, Q8NBI1, Q8WZ90, Q96NF8, Q9H0A7, |
UniProt Related Accession: | Q9BRR6 |
Molecular Weight: | 8,252 Da |
NCBI Full Name: | ADP-dependent glucokinase |
NCBI Synonym Full Names: | ADP-dependent glucokinase |
NCBI Official Symbol: | ADPGK |
NCBI Official Synonym Symbols: | ADP-GK; 2610017G09Rik |
NCBI Protein Information: | ADP-dependent glucokinase; rbBP-35; ATP-dependent glucokinase |
UniProt Protein Name: | ADP-dependent glucokinase |
UniProt Synonym Protein Names: | RbBP-35 |
Protein Family: | ADP-dependent glucokinase |
UniProt Gene Name: | ADPGK |
UniProt Entry Name: | ADPGK_HUMAN |