ADH4 Antibody (PACO15328)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO15328
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | ADH4 Antibody (PACO15328) |
Antibody SKU: | PACO15328 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human ADH4 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO15328(ADH4 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15328(ADH4 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. |
Synonyms: | alcohol dehydrogenase 4 (class II), pi polypeptide |
UniProt Protein Function: | ADH4: class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 1.1.1.1; Xenobiotic Metabolism - metabolism by cytochrome P450; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Amino Acid Metabolism - tyrosine; Oxidoreductase; Lipid Metabolism - fatty acid Chromosomal Location of Human Ortholog: 4q22 Cellular Component: cytosol Molecular Function:zinc ion binding; NADPH:quinone reductase activity; alcohol dehydrogenase activity; all-trans retinal binding; alcohol dehydrogenase activity, zinc-dependent; ethanol binding; aldehyde reductase activity; benzaldehyde dehydrogenase activity; NAD binding; retinol binding; retinol dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Biological Process: retinol metabolic process; xenobiotic metabolic process; alcohol metabolic process; alcohol catabolic process; aldehyde metabolic process; ethanol oxidation; retinoid metabolic process |
NCBI Summary: | This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008] |
UniProt Code: | P08319 |
NCBI GenInfo Identifier: | 308153684 |
NCBI Gene ID: | 127 |
NCBI Accession: | P08319.5 |
UniProt Secondary Accession: | P08319,Q8TCD7, A8K470, B4DIE7, C9J4A9, |
UniProt Related Accession: | P08319 |
Molecular Weight: | 380 |
NCBI Full Name: | Alcohol dehydrogenase 4 |
NCBI Synonym Full Names: | alcohol dehydrogenase 4 (class II), pi polypeptide |
NCBI Official Symbol: | ADH4 |
NCBI Official Synonym Symbols: | ADH-2; HEL-S-4 |
NCBI Protein Information: | alcohol dehydrogenase 4; aldehyde reductase; epididymis secretory protein Li 4; alcohol dehydrogenase class II pi chain |
UniProt Protein Name: | Alcohol dehydrogenase 4 |
UniProt Synonym Protein Names: | Alcohol dehydrogenase class II pi chain |
Protein Family: | Alcohol dehydrogenase |
UniProt Gene Name: | ADH4 |
UniProt Entry Name: | ADH4_HUMAN |