ADCY4 Antibody (PACO15323)
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주문- SKU:
- PACO15323
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | ADCY4 Antibody (PACO15323) |
Antibody SKU: | PACO15323 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human ADCY4 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15323(ADCY4 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15323(ADCY4 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. |
Synonyms: | adenylate cyclase 4 |
UniProt Protein Function: | ADCY4: This is a membrane-bound, calmodulin-insensitive adenylyl cyclase. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. |
UniProt Protein Details: | Protein type:Adenylyl cyclase; EC 4.6.1.1; Lyase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Transporter; Transporter, aquaporin family Chromosomal Location of Human Ortholog: 14q12 Cellular Component: cytoplasm; guanylate cyclase complex, soluble; membrane; plasma membrane Molecular Function:adenylate cyclase activity; guanylate cyclase activity; protein binding Biological Process: activation of protein kinase A; adenylate cyclase activation; cAMP biosynthetic process; cGMP biosynthetic process; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; renal water homeostasis; signal transduction |
NCBI Summary: | This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010] |
UniProt Code: | Q8NFM4 |
NCBI GenInfo Identifier: | 25008336 |
NCBI Gene ID: | 196883 |
NCBI Accession: | Q8NFM4.1 |
UniProt Secondary Accession: | Q8NFM4,Q17R40, Q6ZTM6, Q96ML7, B3KV74, D3DS75, |
UniProt Related Accession: | Q8NFM4 |
Molecular Weight: | 120kDa |
NCBI Full Name: | Adenylate cyclase type 4 |
NCBI Synonym Full Names: | adenylate cyclase 4 |
NCBI Official Symbol: | ADCY4 |
NCBI Official Synonym Symbols: | AC4 |
NCBI Protein Information: | adenylate cyclase type 4 |
UniProt Protein Name: | Adenylate cyclase type 4 |
UniProt Synonym Protein Names: | ATP pyrophosphate-lyase 4; Adenylate cyclase type IV; Adenylyl cyclase 4 |
Protein Family: | Adenylate cyclase |
UniProt Gene Name: | ADCY4 |
Antibodies | ELISA Kits |
Anti-ADCY4 Antibody (CAB10647) | Human ADCY4 (Adenylate Cyclase 4) ELISA Kit (HUES01506) |
ADCY4 Antibody (PACO02628) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |