ACTR3 Antibody (PACO48134)
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주문- SKU:
- PACO48134
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | ACTR3 Antibody (PACO48134) |
Antibody SKU: | PACO48134 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Actin-related protein 3 protein (352-409AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human placental tissue using PACO48134 at dilution of 1:100. | |
Immunofluorescent analysis of Hela cells using PACO48134 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis. |
Synonyms: | Actin-related protein 3 (Actin-like protein 3), ACTR3, ARP3 |
UniProt Protein Function: | Arp3: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis. Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with WHDC1. Belongs to the actin family. ARP3 subfamily. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 2q14.1 Cellular Component: Golgi membrane; Arp2/3 protein complex; focal adhesion; hemidesmosome; membrane; lamellipodium; excitatory synapse; podosome; actin filament; intercellular junction; cytosol; actin cytoskeleton Molecular Function:actin filament binding; protein binding; structural constituent of cytoskeleton; ATP binding Biological Process: response to antibiotic; positive regulation of filopodium formation; axon guidance; meiotic chromosome movement towards spindle pole; asymmetric cell division; regulation of myosin II filament assembly or disassembly; establishment and/or maintenance of cell polarity; ephrin receptor signaling pathway; innate immune response; cytokinesis after meiosis; positive regulation of dendrite morphogenesis; cell motility; response to carbohydrate stimulus; spindle localization |
NCBI Summary: | The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013] |
UniProt Code: | P61158 |
NCBI GenInfo Identifier: | 47117647 |
NCBI Gene ID: | 10096 |
NCBI Accession: | P61158.3 |
UniProt Secondary Accession: | P61158,P32391, Q53QM2, |
UniProt Related Accession: | P61158 |
Molecular Weight: | 47,371 Da |
NCBI Full Name: | Actin-related protein 3 |
NCBI Synonym Full Names: | ARP3 actin-related protein 3 homolog (yeast) |
NCBI Official Symbol: | ACTR3 |
NCBI Official Synonym Symbols: | ARP3 |
NCBI Protein Information: | actin-related protein 3; actin-like protein 3 |
UniProt Protein Name: | Actin-related protein 3 |
UniProt Synonym Protein Names: | Actin-like protein 3 |
UniProt Gene Name: | ACTR3 |
UniProt Entry Name: | ARP3_HUMAN |
Antibodies |
Anti-ACTR3 Antibody (CAB1064) |
Anti-Arp3 Antibody (CAB4514) |
ACTR3 Antibody (PACO06264) |
ACTR3 Antibody (PACO07591) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |