ACO2 Antibody (PACO07452)
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주문- SKU:
- PACO07452
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ACO2 Antibody (PACO07452) |
Antibody SKU: | PACO07452 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:10000-1:20000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from human ACO2. at AA range: 421-470 |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot analysis of 1,mouse-kidney 2,mouse-heart 3,3T3 4,Hela cells using primary antibody diluted at 1:500(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour). |
Synonyms: | Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) |
UniProt Protein Function: | ACO2: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. Monomer. Belongs to the aconitase/IPM isomerase family. |
UniProt Protein Details: | Protein type:Lyase; EC 4.2.1.3; Carbohydrate Metabolism - glyoxylate and dicarboxylate; Carbohydrate Metabolism - citrate (TCA) cycle; Mitochondrial Chromosomal Location of Human Ortholog: 22q13.2 Cellular Component: mitochondrion; mitochondrial matrix; nucleus Molecular Function:iron ion binding; 4 iron, 4 sulfur cluster binding; aconitate hydratase activity; 3 iron, 4 sulfur cluster binding Biological Process: isocitrate metabolic process; cellular metabolic process; generation of precursor metabolites and energy; tricarboxylic acid cycle; citrate metabolic process Disease: Infantile Cerebellar-retinal Degeneration; Optic Atrophy 8 |
NCBI Summary: | The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99798 |
NCBI GenInfo Identifier: | 6686275 |
NCBI Gene ID: | 50 |
NCBI Accession: | Q99798.2 |
UniProt Related Accession: | Q99798 |
Molecular Weight: | |
NCBI Full Name: | Aconitate hydratase, mitochondrial |
NCBI Synonym Full Names: | aconitase 2 |
NCBI Official Symbol: | ACO2 |
NCBI Official Synonym Symbols: | ICRD; OCA8; OPA9; ACONM; HEL-S-284 |
NCBI Protein Information: | aconitate hydratase, mitochondrial |
UniProt Protein Name: | Aconitate hydratase, mitochondrial |
UniProt Synonym Protein Names: | Citrate hydro-lyase |
Protein Family: | Aconitate hydratase |
UniProt Gene Name: | ACO2 |
UniProt Entry Name: | ACON_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |